PMID- 12527979
OWN - NLM
STAT- MEDLINE
DCOM- 20030721
LR  - 20131121
IS  - 1439-6319 (Print)
IS  - 1439-6319 (Linking)
VI  - 88
IP  - 4-5
DP  - 2003 Jan
TI  - Effects of pre-exercise ingestion of carbohydrate on glycaemic and insulinaemic 
      responses during subsequent exercise at differing intensities.
PG  - 466-71
AB  - The development of rebound hypoglycaemia has been reported after pre-exercise 
      carbohydrate (CHO) ingestion in some studies but not in others. Differences in 
      the experimental design and factors such as the exercise intensity are likely to 
      be responsible for the discrepancies between these studies. Exercise intensity 
      might be a crucial factor since it affects both insulinaemia and glucose uptake. 
      Therefore the aim of the present study was to compare the glycaemic and 
      insulinaemic responses to exercise at different intensities after ingestion of a 
      standardized pre-exercise CHO load. Eight moderately trained subjects consumed 75 
      g of glucose 45 min prior to 20 min of exercise at 40%, 65% or 80% maximal power 
      output. Blood samples were collected before glucose ingestion, at 15 min 
      intervals at rest and 5 min intervals during exercise. During exercise, 
      measurements of heart rate and breath-by-breath analysis of expired gas were 
      performed continuously. The trials were performed at [mean (SEM)] 55 (1), 77 (1) 
      and 90 (1) percentages maximal oxygen uptake. At the onset of exercise, plasma 
      glucose concentration returned to pre-ingestion levels, while the insulin 
      concentration was more than three times higher than at rest [on average 57 (7) 
      compared to 16 (1) microU.ml(-1)]. During exercise, plasma glucose concentrations 
      decreased during the first 5 min of exercise and then stabilized in all trials at 
      concentrations that would not be considered to be hypoglycaemic. There were no 
      significant differences in glucose or insulin concentrations between the three 
      trials during exercise. These data suggest that the glycaemic response to 
      ingestion of 75 g of CHO 45 min pre-exercise is similar during exercise of 
      different intensities.
FAU - Achten, Juul
AU  - Achten J
AD  - Human Performance Laboratory, School of Sport and Exercise Sciences, University 
      of Birmingham, Edgbaston, B15 2TT, Birmingham, UK. A.E.Jeukendrup@bham.ac.uk
FAU - Jeukendrup, Asker E
AU  - Jeukendrup AE
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20021127
PL  - Germany
TA  - Eur J Appl Physiol
JT  - European journal of applied physiology
JID - 100954790
RN  - 0 (Blood Glucose)
RN  - 0 (Insulin)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Adult
MH  - Bicycling/*physiology
MH  - Blood Glucose/*analysis
MH  - Drug Administration Schedule
MH  - Glucose/*administration & dosage
MH  - Humans
MH  - Insulin/*blood
MH  - Male
MH  - Osmolar Concentration
MH  - Physical Exertion
EDAT- 2003/01/16 04:00
MHDA- 2003/07/23 05:00
CRDT- 2003/01/16 04:00
PHST- 2002/04/15 00:00 [accepted]
PHST- 2003/01/16 04:00 [pubmed]
PHST- 2003/07/23 05:00 [medline]
PHST- 2003/01/16 04:00 [entrez]
AID - 10.1007/s00421-002-0730-1 [doi]
PST - ppublish
SO  - Eur J Appl Physiol. 2003 Jan;88(4-5):466-71. doi: 10.1007/s00421-002-0730-1. Epub 
      2002 Nov 27.