PMID- 12531511
OWN - NLM
STAT- MEDLINE
DCOM- 20030701
LR  - 20190826
IS  - 0169-328X (Print)
IS  - 0169-328X (Linking)
VI  - 109
IP  - 1-2
DP  - 2002 Dec 30
TI  - Differential expressions of mPer1 and mPer2 mRNAs under a skeleton photoperiod 
      and a complete light-dark cycle.
PG  - 11-7
AB  - To investigate the molecular mechanisms in photo-entrainment of circadian 
      rhythms, expression patterns of mouse period1 (mPer1) and mPer2 mRNAs were 
      examined in the suprachiasmatic nucleus (SCN) and skin under a complete 
      light-dark (LD) cycle and a corresponding skeleton photoperiod (SPP). Under the 
      SPP, the robust daily expressions of mPer1 and mPer2 were maintained in the SCN 
      and in the skin. A slower rise time for mPer1 mRNA expression was observed in the 
      SPP compared with that in the LD condition both in the SCN and in the skin, 
      although the expression pattern of mPer2 was not significantly different between 
      the two lighting conditions. The results suggest that the expressions of mPer1 
      and mPer2 mRNAs are differentially regulated not only in the SCN but also in 
      peripheral tissues. Furthermore, we propose that the persistent expression of 
      mPer2 mRNA is required for the entrainment to the SPP.
FAU - Oishi, Katsutaka
AU  - Oishi K
AD  - Clock Cell Biology Group, National Institute of Advanced Industrial Science and 
      Technology, Central 6, 1-1-1, Higashi, Tsukuba, Ibaraki 305-8566, Japan.
FAU - Fukui, Hiromi
AU  - Fukui H
FAU - Sakamoto, Katsuhiko
AU  - Sakamoto K
FAU - Miyazaki, Koyomi
AU  - Miyazaki K
FAU - Kobayashi, Hisato
AU  - Kobayashi H
FAU - Ishida, Norio
AU  - Ishida N
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Brain Res Mol Brain Res
JT  - Brain research. Molecular brain research
JID - 8908640
RN  - 0 (Cell Cycle Proteins)
RN  - 0 (Nuclear Proteins)
RN  - 0 (Per1 protein, mouse)
RN  - 0 (Per2 protein, mouse)
RN  - 0 (Period Circadian Proteins)
RN  - 0 (Transcription Factors)
SB  - IM
MH  - Animals
MH  - Behavior, Animal/physiology
MH  - Cell Cycle Proteins
MH  - Circadian Rhythm/*physiology
MH  - Darkness
MH  - Gene Expression Regulation
MH  - Light
MH  - Male
MH  - Mice
MH  - Nuclear Proteins/genetics/*metabolism
MH  - Period Circadian Proteins
MH  - *Photoperiod
MH  - Skin/metabolism
MH  - Suprachiasmatic Nucleus/cytology/metabolism
MH  - Transcription Factors
EDAT- 2003/01/18 04:00
MHDA- 2003/07/02 05:00
CRDT- 2003/01/18 04:00
PHST- 2003/01/18 04:00 [pubmed]
PHST- 2003/07/02 05:00 [medline]
PHST- 2003/01/18 04:00 [entrez]
AID - S0169328X02004576 [pii]
AID - 10.1016/s0169-328x(02)00457-6 [doi]
PST - ppublish
SO  - Brain Res Mol Brain Res. 2002 Dec 30;109(1-2):11-7. doi: 
      10.1016/s0169-328x(02)00457-6.