PMID- 12544960 OWN - NLM STAT- MEDLINE DCOM- 20030205 LR - 20220311 IS - 1528-1159 (Electronic) IS - 0362-2436 (Linking) VI - 28 IP - 1 DP - 2003 Jan 1 TI - Discrimination validity of the scoliosis research society-22 patient questionnaire: relationship to idiopathic scoliosis curve pattern and curve size. PG - 74-8 AB - STUDY DESIGN: Prospective observational study. OBJECTIVE: To determine the discriminant validity of the Scoliosis Research Society-22 (SRS-22) health-related quality-of-life (HRQL) questionnaire for idiopathic scoliosis patients based on curve pattern and curve size. SUMMARY OF BACKGROUND DATA: An important psychometric attribute of the HRQL questionnaire is the capacity to discriminate between and among patients with differing condition severity. METHOD: Three study groups, with subjects ranging in age from 10 to 16 years, were set up: a control group (C) of 19 persons with scoliosis suspected but unproven with an average age of 13 years; a nonsurgical group (NS) of 68 patients with an average age of 14 years and an average scoliosis (Cobb) of 30 degrees; and a presurgical group (PS) of 32 patients with an average age of 14 years and an average scoliosis of 61 degrees. The NS group was subdivided into untreated (NSU) (n = 54) and braced (NSB) patients (n = 14). Also created were subgroups of the NS and PS groups having similar curve sizes: nonsurgical similar (NSS) and presurgery similar (PSS). Statistical significance of the SRS-22 domain scores by comparison groups was tested by ANOVA. Relationships between the SRS-22 questionnaire and scoliosis deformity measurements were calculated using the Pearson Correlation Coefficients. RESULTS: There were no significant differences between the control (C) and nonsurgical (NS) groups. The presurgical group (PS) scored significantly lower in the pain and self-image domains than the C or NS groups and lower than group C in the mental health domain. A subgroup of the nonsurgical group (NSS) with curves comparable to the presurgical subgroup (PSS) had significantly better self-image scores. There were no significant correlations between SRS-22 scores and curve pattern. For persons with scoliosis, curve size (Cobb) correlated with pain, self-image, and function; trunk asymmetry correlated with self-image. CONCLUSION: The SRS-22 HRQL questionnaire successfully discriminated among persons with no scoliosis or moderate scoliosis and large scoliosis. It did not discriminate among patients with single, double, or triple curves. Self-image and, to a lesser extent, pain and function domain scores correlated with radiographic and trunk asymmetry severity. The SRS-22 HRQL questionnaire may be useful in choosing nonsurgical versus surgical treatment in borderline cases. FAU - Asher, Marc AU - Asher M AD - School of Medicine, Section of Orthopedic Surgery, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160-7387, USA. masher@kumc.edu. FAU - Min Lai, Sue AU - Min Lai S FAU - Burton, Doug AU - Burton D FAU - Manna, Barbara AU - Manna B LA - eng PT - Comparative Study PT - Journal Article PT - Validation Study PL - United States TA - Spine (Phila Pa 1976) JT - Spine JID - 7610646 SB - IM CIN - Spine (Phila Pa 1976). 2003 Jan 1;28(1):77-8. PMID: 12544961 MH - Adolescent MH - Analysis of Variance MH - Braces MH - Child MH - Discriminant Analysis MH - Female MH - Humans MH - Male MH - Outcome Assessment, Health Care/*methods/statistics & numerical data MH - Predictive Value of Tests MH - Prospective Studies MH - Quality of Life MH - Reproducibility of Results MH - Scoliosis/*classification/*diagnosis/therapy MH - Sensitivity and Specificity MH - *Sickness Impact Profile MH - Societies, Medical/*standards MH - Surveys and Questionnaires/*standards EDAT- 2003/01/25 04:00 MHDA- 2003/02/06 04:00 CRDT- 2003/01/25 04:00 PHST- 2003/01/25 04:00 [pubmed] PHST- 2003/02/06 04:00 [medline] PHST- 2003/01/25 04:00 [entrez] AID - 10.1097/00007632-200301010-00017 [doi] PST - ppublish SO - Spine (Phila Pa 1976). 2003 Jan 1;28(1):74-8. doi: 10.1097/00007632-200301010-00017.