PMID- 12559635 OWN - NLM STAT- MEDLINE DCOM- 20030926 LR - 20221207 IS - 0198-8859 (Print) IS - 0198-8859 (Linking) VI - 64 IP - 2 DP - 2003 Feb TI - A new HLA-DRB allele (DRB1*15014) identified in a Caucasian individual. PG - 310-3 AB - Polymerase chain reaction with sequence specific primers subtyping of a DRB1*15 allele in a male 11-year-old German Caucasian and his father revealed a reaction pattern that did not agree with any known specificity, thus suggesting the existence of a novel allele. Sequence-based typing after allelic separation revealed the new allele human leukocyte antigen (HLA)-DRB1*15014. The sequence pattern of HLA-DRB1*15014 might have been generated as a result of two independent recombinations, most likely over several generations. FAU - Czachurski, Daniel AU - Czachurski D AD - Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Germany. FAU - Opelz, Gerhard AU - Opelz G FAU - Mytilineos, Joannis AU - Mytilineos J LA - eng PT - Comparative Study PT - Journal Article PL - United States TA - Hum Immunol JT - Human immunology JID - 8010936 RN - 0 (HLA-DR Antigens) RN - 0 (HLA-DRB1 Chains) SB - IM MH - Adult MH - *Alleles MH - Asian People/genetics MH - Base Sequence MH - Child MH - Gene Frequency MH - *Genes, MHC Class II MH - HLA-DR Antigens/*genetics MH - HLA-DRB1 Chains MH - Humans MH - Male MH - Molecular Sequence Data MH - Polymerase Chain Reaction MH - Sequence Alignment MH - Sequence Analysis, DNA MH - Sequence Homology, Nucleic Acid MH - White People/*genetics EDAT- 2003/02/01 04:00 MHDA- 2003/09/27 05:00 CRDT- 2003/02/01 04:00 PHST- 2003/02/01 04:00 [pubmed] PHST- 2003/09/27 05:00 [medline] PHST- 2003/02/01 04:00 [entrez] AID - S0198885902007796 [pii] AID - 10.1016/s0198-8859(02)00779-6 [doi] PST - ppublish SO - Hum Immunol. 2003 Feb;64(2):310-3. doi: 10.1016/s0198-8859(02)00779-6.