PMID- 12564871
OWN - NLM
STAT- MEDLINE
DCOM- 20030506
LR  - 20061115
IS  - 0278-0062 (Print)
IS  - 0278-0062 (Linking)
VI  - 21
IP  - 9
DP  - 2002 Sep
TI  - Model-based imaging of cardiac electrical excitation in humans.
PG  - 1031-9
AB  - Activation time (AT) imaging from electrocardiographic (ECG) mapping data has 
      been developing for several years. By coupling ECG mapping and three-dimensional 
      (3-D) + time anatomical data, the electrical excitation sequence can be imaged 
      completely noninvasively in the human heart. In this paper, a bidomain 
      theory-based surface heart model AT imaging approach was applied to single-beat 
      data of atrial and ventricular depolarization in two patients with structurally 
      normal hearts. In both patients, the AT map was reconstructed from sinus and 
      paced rhythm data. Pacing sites were the apex of the right ventricle and the 
      coronary sinus (CS) ostium. For CS pacing, the reconstructed AT pattern on the 
      endocardium of the right atrium was compared with the CARTO map in both patients. 
      The localization errors of the origins of the initial endocardial breakthroughs 
      were determined to be 6 and 12 mm. The sites of early activation and the areas 
      with late activation were estimated with sufficient accuracy. The reconstructed 
      sinus rhythm sequence was in good qualitative agreement with the pattern 
      previously published for the isolated Langendorff-perfused human heart.
FAU - Tilg, Bernhard
AU  - Tilg B
AD  - Institute of Biomedical Engineering, Graz University of Technology. 
      bernhard.tilg@umit.at
FAU - Fischer, Gerald
AU  - Fischer G
FAU - Modre, Robert
AU  - Modre R
FAU - Hanser, Friedrich
AU  - Hanser F
FAU - Messnarz, Bernd
AU  - Messnarz B
FAU - Schocke, Michael
AU  - Schocke M
FAU - Kremser, Christian
AU  - Kremser C
FAU - Berger, Thomas
AU  - Berger T
FAU - Hintringer, Florian
AU  - Hintringer F
FAU - Roithinger, Franz Xaver
AU  - Roithinger FX
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - IEEE Trans Med Imaging
JT  - IEEE transactions on medical imaging
JID - 8310780
SB  - IM
MH  - Adult
MH  - Aged
MH  - Atrial Flutter/physiopathology
MH  - Cardiac Pacing, Artificial
MH  - *Electrocardiography
MH  - *Electrophysiologic Techniques, Cardiac
MH  - Female
MH  - Heart Atria
MH  - Heart Ventricles
MH  - Humans
MH  - *Imaging, Three-Dimensional
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Wolff-Parkinson-White Syndrome/physiopathology
EDAT- 2003/02/05 04:00
MHDA- 2003/05/07 05:00
CRDT- 2003/02/05 04:00
PHST- 2003/02/05 04:00 [pubmed]
PHST- 2003/05/07 05:00 [medline]
PHST- 2003/02/05 04:00 [entrez]
AID - 10.1109/TMI.2002.804438 [doi]
PST - ppublish
SO  - IEEE Trans Med Imaging. 2002 Sep;21(9):1031-9. doi: 10.1109/TMI.2002.804438.