PMID- 12575335
OWN - NLM
STAT- MEDLINE
DCOM- 20030310
LR  - 20131121
IS  - 1000-5625 (Print)
IS  - 1000-5625 (Linking)
VI  - 27
IP  - 2
DP  - 2002 Apr 28
TI  - [Experimental study on the viricidal effect of rough extracts of camptothecine 
      fruit on herpes simplex virus-2 in vitro].
PG  - 121-2
AB  - OBJECTIVE: To study the viricidal effect of rough extracts of camptothecine fruit 
      on herpes simplex virus-2 (HSV-2). METHODS: Rough extracts with different 
      concentrations were mixed with HSV-2. The mixture was incubated at 37 degrees C 
      for 4 h or at 4 degrees C overnight, adsorbed on monolayer cells of BGM for 1.5 
      h, and cultured at 37 degrees C for 7 d. RESULTS: The BGM of the test group did 
      not reveal cytopathic effects (CPE), while the control group showed CPE under 
      microscope observation. CONCLUSION: Camptothecine has a strong viricidal effect 
      on HSV-2.
FAU - Li, Wen-wen
AU  - Li WW
AD  - Department of Clinical Microbiology and Immunology, Xiangya School of Medicine, 
      Central South University, Changsha 410078, China.
FAU - Yan, Zu-wei
AU  - Yan ZW
FAU - Shi, Kai
AU  - Shi K
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Hunan Yi Ke Da Xue Xue Bao
JT  - Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical 
      University
JID - 9424769
RN  - 0 (Antiviral Agents)
RN  - 0 (Plant Extracts)
RN  - XT3Z54Z28A (Camptothecin)
SB  - IM
MH  - Antiviral Agents/*pharmacology
MH  - Camptotheca/*chemistry
MH  - Camptothecin/*pharmacology
MH  - Fruit/chemistry
MH  - Herpesvirus 2, Human/*drug effects
MH  - Humans
MH  - Plant Extracts/pharmacology
EDAT- 2003/02/11 04:00
MHDA- 2003/03/11 04:00
CRDT- 2003/02/11 04:00
PHST- 2003/02/11 04:00 [pubmed]
PHST- 2003/03/11 04:00 [medline]
PHST- 2003/02/11 04:00 [entrez]
PST - ppublish
SO  - Hunan Yi Ke Da Xue Xue Bao. 2002 Apr 28;27(2):121-2.