PMID- 12576906
OWN - NLM
STAT- MEDLINE
DCOM- 20030528
LR  - 20220316
IS  - 0883-9212 (Print)
IS  - 0883-9212 (Linking)
VI  - 23
IP  - 1
DP  - 2003 Jan-Feb
TI  - Exercise training for heart failure patients improves respiratory muscle 
      endurance, exercise tolerance, breathlessness, and quality of life.
PG  - 10-6
AB  - PURPOSE: Increased respiratory muscle endurance and peak oxygen consumption 
      (VO(2peak)) induced by respiratory muscle training support the relationship 
      between respiratory muscle function and exercise capacity in patients with heart 
      failure. This raises the question whether exercise-training results in increased 
      respiratory muscle function contributing to an increased exercise tolerance, a 
      decreased perception of breathlessness, and an improved quality of life. METHODS: 
      Prospective cohort analysis was completed on 24 patients with New York Heart 
      Association (NYHA) Class III heart failure [18 men, 6 women; aged = 64 (SD 7.9) 
      years; percent ejection fraction (%EF) = 24.0 (SD 7.8)]. Maximal sustainable 
      ventilatory capacity (MSVC), submaximal and peak exercise responses, perception 
      of breathlessness, and quality of life were measured before (baseline) and after 
      (end of study) 12 weeks of exercise training. RESULTS: As a result of exercise 
      training, VO(2peak) (P=.01) and MSVC (P<.001) increased, with MSVC contributing 
      to a larger proportion of the variability for VO(2peak) at study completion 
      (r=0.57 vs 0.42). Although stroke volume did not increase beyond exercise at 25 W 
      and did not change with exercise training, ventilation decreased during exercise 
      (P<.05), perception of breathing difficulty (P<.05) was reduced, and quality of 
      life was enhanced (P=.008). CONCLUSIONS: Despite no increase in cardiac output 
      and stroke volume, respiratory muscle endurance improved with exercise training, 
      contributing to increased exercise capacity, decreased breathlessness, and 
      decreased perception of breathlessness. Practical implications can include less 
      frequent rest periods and fatigue, greater confidence, maintenance of 
      independence, and enhanced quality of life.
FAU - McConnell, Timothy R
AU  - McConnell TR
AD  - Department of Cardiology, Geisinger Medical Center, Danville, PA 17822-2160, USA. 
      tmcconnell@geisinger.edu
FAU - Mandak, Jeffrey S
AU  - Mandak JS
FAU - Sykes, Jeffrey S
AU  - Sykes JS
FAU - Fesniak, Henry
AU  - Fesniak H
FAU - Dasgupta, Himadri
AU  - Dasgupta H
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Cardiopulm Rehabil
JT  - Journal of cardiopulmonary rehabilitation
JID - 8511296
SB  - IM
MH  - Aged
MH  - Analysis of Variance
MH  - Cohort Studies
MH  - Dyspnea/*prevention & control
MH  - *Exercise Therapy
MH  - Exercise Tolerance/*physiology
MH  - Female
MH  - Heart Failure/diagnosis/*rehabilitation
MH  - Heart Function Tests
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Oxygen Consumption/physiology
MH  - Physical Endurance
MH  - Probability
MH  - Prospective Studies
MH  - *Quality of Life
MH  - Respiratory Function Tests
MH  - Respiratory Muscles/*physiology
MH  - Sensitivity and Specificity
MH  - Severity of Illness Index
EDAT- 2003/02/11 04:00
MHDA- 2003/05/29 05:00
CRDT- 2003/02/11 04:00
PHST- 2003/02/11 04:00 [pubmed]
PHST- 2003/05/29 05:00 [medline]
PHST- 2003/02/11 04:00 [entrez]
AID - 10.1097/00008483-200301000-00003 [doi]
PST - ppublish
SO  - J Cardiopulm Rehabil. 2003 Jan-Feb;23(1):10-6. doi: 
      10.1097/00008483-200301000-00003.