PMID- 12598967
OWN - NLM
STAT- MEDLINE
DCOM- 20030501
LR  - 20041117
IS  - 0179-0358 (Print)
IS  - 0179-0358 (Linking)
VI  - 18
IP  - 8
DP  - 2002 Dec
TI  - Factors effecting morbidity in typhoid intestinal perforation in children.
PG  - 696-700
AB  - To determine the factors affecting morbidity in patients with typhoid intestinal 
      perforation (TIP), 42 patients who had been operated upon for TIP between 1990 
      and 2000 were reviewed. The average age was 10.4 years, the male-to-female ratio 
      2.5/1. The mean interval from admission to operation was 6 h. Twenty-three 
      children had multiple perforations. Primary closure (PC) was performed in 55% of 
      the patients, ileostomy in 26%, and resection with anastomosis (RA) in 19%. 
      Parenteral nutrition (PN) was available for 22 patients for an average of 9 days. 
      Postoperative complications occurred more commonly in patients with delayed 
      admission and/or severe peritonitis. Hospitalization was shorter and the 
      postoperative complication rate lower in patients who received PN and in those 
      who underwent ileostomy. None of the patients developed an enterocutaneous 
      fistula. The 2 deaths (4.8%) resulted from overwhelming sepsis. The most 
      significant factors affecting morbidity were prolongation of 
      perforation-operation interval and severe peritonitis. No operative procedure is 
      likely to be the best in all cases; therapy should be individualized. Ileostomy 
      appears to be an effective procedure, particularly in patients with severe 
      abdominal contamination and delayed presentation. The use of PN in addition to 
      standard medical and surgical therapy in patients with TIP may be beneficial.
FAU - Onen, Abdurrahman
AU  - Onen A
AD  - Department of Pediatric Surgery, Medical Faculty of Dicle University, Diyarbakir, 
      Turkey. aonenmd@yahoo.com
FAU - Dokucu, Ali Ihsan
AU  - Dokucu AI
FAU - Cigdem, Murat Kemal
AU  - Cigdem MK
FAU - Ozturk, Hayrettin
AU  - Ozturk H
FAU - Otcu, Selcuk
AU  - Otcu S
FAU - Yucesan, Selcuk
AU  - Yucesan S
LA  - eng
PT  - Journal Article
DEP - 20021220
PL  - Germany
TA  - Pediatr Surg Int
JT  - Pediatric surgery international
JID - 8609169
SB  - IM
MH  - Adolescent
MH  - Chi-Square Distribution
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Humans
MH  - Intestinal Perforation/*etiology/mortality/*surgery
MH  - Male
MH  - Parenteral Nutrition
MH  - Postoperative Complications/mortality
MH  - Statistics, Nonparametric
MH  - Treatment Outcome
MH  - Typhoid Fever/*complications
EDAT- 2003/02/25 04:00
MHDA- 2003/05/02 05:00
CRDT- 2003/02/25 04:00
PHST- 2001/12/13 00:00 [accepted]
PHST- 2003/02/25 04:00 [pubmed]
PHST- 2003/05/02 05:00 [medline]
PHST- 2003/02/25 04:00 [entrez]
AID - 10.1007/s00383-002-0794-3 [doi]
PST - ppublish
SO  - Pediatr Surg Int. 2002 Dec;18(8):696-700. doi: 10.1007/s00383-002-0794-3. Epub 
      2002 Dec 20.