PMID- 12607168
OWN - NLM
STAT- MEDLINE
DCOM- 20030520
LR  - 20220408
IS  - 1380-3395 (Print)
IS  - 1380-3395 (Linking)
VI  - 25
IP  - 1
DP  - 2003 Feb
TI  - Verbal memory impairment in congestive heart failure.
PG  - 14-23
AB  - Cognitive dysfunction, mainly memory impairment, characterizes congestive heart 
      failure (CHF). Aim of this study was to verify whether: (1) CHF has differential 
      effects on primary and secondary memory; (2) memory dysfunction can be diagnosed 
      by a screening instrument. In a multicenter study we enrolled 369 patients with 
      stable CHF who underwent a structured assessment of verbal memory mechanisms and 
      selected cognitive functions. Performance on some verbal memory indexes (Recency, 
      Rey's immediate and delayed recall, Learning efficiency) progressively decreased 
      from II to IV New York Heart Association (NYHA) class. Rate of forgetting was 
      uniformly high across NYHA classes II-IV. Verbal memory indexes were highly 
      correlated with most nonverbal scores. The Mini Mental State Examination (MMSE) 
      had poor sensitivity and specificity versus primary or secondary verbal memory 
      dysfunction. Therefore, a deficit of both primary and secondary memory is 
      relatively common in CHF but cannot be accurately recognized by a screening 
      neuropsychological test.
FAU - Antonelli Incalzi, R
AU  - Antonelli Incalzi R
AD  - Institute of Internal Medicine, Policlinico Gemelli, School of Medicine, Rome, 
      Italy.
FAU - Trojano, L
AU  - Trojano L
FAU - Acanfora, D
AU  - Acanfora D
FAU - Crisci, C
AU  - Crisci C
FAU - Tarantino, F
AU  - Tarantino F
FAU - Abete, P
AU  - Abete P
FAU - Rengo, F
AU  - Rengo F
CN  - CHF Italian Study Investigators
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
PL  - England
TA  - J Clin Exp Neuropsychol
JT  - Journal of clinical and experimental neuropsychology
JID - 8502170
SB  - IM
MH  - Activities of Daily Living
MH  - Aged
MH  - Aged, 80 and over
MH  - Analysis of Variance
MH  - Cognition
MH  - Disease Progression
MH  - Female
MH  - Heart Failure/*complications/psychology
MH  - Humans
MH  - Male
MH  - Memory Disorders/*etiology/physiopathology
MH  - Mental Recall
MH  - Mental Status Schedule/statistics & numerical data
MH  - ROC Curve
MH  - Verbal Learning/*physiology
MH  - Word Association Tests
EDAT- 2003/02/28 04:00
MHDA- 2003/05/21 05:00
CRDT- 2003/02/28 04:00
PHST- 2003/02/28 04:00 [pubmed]
PHST- 2003/05/21 05:00 [medline]
PHST- 2003/02/28 04:00 [entrez]
AID - 10.1076/jcen.25.1.14.13635 [doi]
PST - ppublish
SO  - J Clin Exp Neuropsychol. 2003 Feb;25(1):14-23. doi: 10.1076/jcen.25.1.14.13635.