PMID- 12614407 OWN - NLM STAT- MEDLINE DCOM- 20030602 LR - 20190813 IS - 0013-9580 (Print) IS - 0013-9580 (Linking) VI - 44 IP - 3 DP - 2003 Mar TI - Successful neurosurgical treatment of childhood complex partial status epilepticus with focal resection. PG - 468-71 AB - The treatment of complex partial status epilepticus continues to be controversial, especially with regard to the intensity of the treatment. Medical therapy and drug-induced coma are sometimes required. Rarely this may not be effective. A healthy 4-year old girl was first seen in complex partial status epilepticus. She had a 1-year history of cryptogenic partial-onset seizures. Detailed magnetic resonance imaging (MRI) studies were normal. Her course was refractory to multiple medical therapies and multiple subpial transection (MST). An urgent epilepsy surgery evaluation resulted in a focal cortical resection being performed over the right mesial parietal region with resultant seizure freedom and no significant neurologic deficit 2 years later. This patient illustrates the need to consider occult focal cortical dysplasia as a cause of nonconvulsive status epilepticus (NCSE) in children, and if it is not responsive to medical management, the utility of performing an urgent epilepsy surgery evaluation. FAU - Ng, Yu-tze AU - Ng YT AD - Texas Comprehensive Epilepsy Program, Department of Neurology, University of Texas-Houston Medical School, Houston, Texas, USA. y2ng@chw.edu FAU - Kim, Howard L AU - Kim HL FAU - Wheless, James W AU - Wheless JW LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Epilepsia JT - Epilepsia JID - 2983306R SB - IM MH - Brain Mapping MH - Child, Preschool MH - Electrodes, Implanted MH - Electroencephalography/methods/statistics & numerical data MH - Female MH - Functional Laterality/physiology MH - Humans MH - Magnetic Resonance Imaging MH - Magnetoencephalography MH - Nervous System Malformations/diagnosis/surgery MH - Parietal Lobe/abnormalities/*surgery MH - Status Epilepticus/diagnosis/*surgery MH - Treatment Outcome EDAT- 2003/03/05 04:00 MHDA- 2003/06/05 05:00 CRDT- 2003/03/05 04:00 PHST- 2003/03/05 04:00 [pubmed] PHST- 2003/06/05 05:00 [medline] PHST- 2003/03/05 04:00 [entrez] AID - epi40302 [pii] AID - 10.1046/j.1528-1157.2003.40302.x [doi] PST - ppublish SO - Epilepsia. 2003 Mar;44(3):468-71. doi: 10.1046/j.1528-1157.2003.40302.x.