PMID- 12623948
OWN - NLM
STAT- MEDLINE
DCOM- 20030411
LR  - 20220408
IS  - 1524-4563 (Electronic)
IS  - 0194-911X (Linking)
VI  - 41
IP  - 3
DP  - 2003 Mar
TI  - Association between periodontal disease and left ventricle mass in essential 
      hypertension.
PG  - 488-92
AB  - Chronic periodontitis has been associated with an increased risk for 
      cardiovascular disease. Left ventricular mass is an established independent 
      predictor of cardiovascular disease. In the present cross-sectional study, we 
      tested the association between periodontitis and left ventricular mass in 
      subjects with essential hypertension. One hundred four untreated subjects with 
      essential hypertension underwent clinical examinations, including 
      echocardiographic study, laboratory tests, and assessment of periodontal status 
      according to the community periodontal index of treatment needs (CPITN). With 
      increasing severity of periodontitis, there was a progressive increase in left 
      ventricle mass. Mean values (g/height2.7) were 39.0 (+/-2.7) in CPITN 0 
      (periodontal health), 40.2 (+/-6.4) in CPITN 1 (gingival bleeding), 42.7 (+/-6.8) 
      in CPITN 2 (calculus), 51.4 (+/-11.7) in CPITN 3 (pockets 4 to 5 mm), and 76.7 
      (+/-11.3) in CPITN 4 (pockets > or =6 mm) (overall F 51.2; P<0.0001). Body 
      surface area (P=0.04), systolic (P<0.0001) and diastolic (P<0.01) blood pressure, 
      and left ventricular mass (P<0.0001) were determinants of a composite of CPITN 3 
      and 4. In a multivariate logistic analysis, left ventricular mass was the sole 
      determinant (P<0.0001) of CPITN stages 3 and 4. Our findings suggest a direct 
      association between severity of periodontitis and left ventricular mass in 
      subjects with essential hypertension. Periodontal evaluation might contribute to 
      refine cardiovascular risk assessment in hypertensive subjects.
FAU - Angeli, Fabio
AU  - Angeli F
AD  - Dipartimento Malattie Cardiovascolari, Universita degli Studi di Perugia and 
      Ospedale R. Silvestrini, Perugia, Italy. fangeli@cardionet.it
FAU - Verdecchia, Paolo
AU  - Verdecchia P
FAU - Pellegrino, Concetta
AU  - Pellegrino C
FAU - Pellegrino, Rosaria Giulia
AU  - Pellegrino RG
FAU - Pellegrino, Giacinto
AU  - Pellegrino G
FAU - Prosciutti, Lucio
AU  - Prosciutti L
FAU - Giannoni, Claudia
AU  - Giannoni C
FAU - Cianetti, Stefano
AU  - Cianetti S
FAU - Bentivoglio, Maurizio
AU  - Bentivoglio M
LA  - eng
PT  - Journal Article
DEP - 20030210
PL  - United States
TA  - Hypertension
JT  - Hypertension (Dallas, Tex. : 1979)
JID - 7906255
SB  - IM
MH  - Cardiovascular Diseases/etiology
MH  - Cross-Sectional Studies
MH  - Female
MH  - Heart Ventricles/*diagnostic imaging
MH  - Humans
MH  - Hypertension/*complications/diagnosis
MH  - Hypertrophy, Left Ventricular/complications/diagnostic imaging
MH  - Male
MH  - Middle Aged
MH  - Periodontal Diseases/*complications/diagnosis
MH  - Risk Factors
MH  - Ultrasonography
EDAT- 2003/03/08 04:00
MHDA- 2003/04/12 05:00
CRDT- 2003/03/08 04:00
PHST- 2003/03/08 04:00 [pubmed]
PHST- 2003/04/12 05:00 [medline]
PHST- 2003/03/08 04:00 [entrez]
AID - 01.HYP.0000056525.17476.D7 [pii]
AID - 10.1161/01.HYP.0000056525.17476.D7 [doi]
PST - ppublish
SO  - Hypertension. 2003 Mar;41(3):488-92. doi: 10.1161/01.HYP.0000056525.17476.D7. 
      Epub 2003 Feb 10.