PMID- 12625413
OWN - NLM
STAT- MEDLINE
DCOM- 20030924
LR  - 20190906
IS  - 0918-8959 (Print)
IS  - 0918-8959 (Linking)
VI  - 49
IP  - 6
DP  - 2002 Dec
TI  - Pituitary adenomas in adolescent patients with multiple endocrine neoplasia type 
      1.
PG  - 635-40
AB  - Two juvenile patients with multiple endocrine neoplasia type 1 (MEN1) who 
      developed pituitary adenomas are reported. The first case, a 14-year-old girl, 
      developed prolactinoma and manifested delayed puberty and growth arrest. The 
      second case, a 16-year-old boy, was asymptomatic and a pituitary adenoma 
      accompanied by mild elevation of PRL and GH was identified through family 
      screening. His growth and pubertal development was not impaired. Medication with 
      bromocriptine was started for both cases with good therapeutic responses. These 
      cases emphasize relevance of early screening of endocrine disorders for members 
      of families with MEN1.
FAU - Oiwa, Ako
AU  - Oiwa A
AD  - Department of Aging Medicine and Geriatrics, Shinshu University School of 
      Medicine, Matsumoto 390-8621, Japan.
FAU - Sakurai, Akihiro
AU  - Sakurai A
FAU - Sato, Yoshihiko
AU  - Sato Y
FAU - Sakuma, Takahiro
AU  - Sakuma T
FAU - Yamashita, Koh
AU  - Yamashita K
FAU - Katai, Miyuki
AU  - Katai M
FAU - Aizawa, Toru
AU  - Aizawa T
FAU - Hashizume, Kiyoshi
AU  - Hashizume K
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - Endocr J
JT  - Endocrine journal
JID - 9313485
RN  - 0 (Hormone Antagonists)
RN  - 3A64E3G5ZO (Bromocriptine)
SB  - IM
MH  - Adolescent
MH  - Bromocriptine/therapeutic use
MH  - Female
MH  - Hormone Antagonists/therapeutic use
MH  - Humans
MH  - Male
MH  - Multiple Endocrine Neoplasia Type 1/diagnosis/drug therapy/*genetics
MH  - Pedigree
MH  - Pituitary Neoplasms/*diagnosis/drug therapy/*genetics
MH  - Prolactinoma/*diagnosis/drug therapy/*genetics
EDAT- 2003/03/11 04:00
MHDA- 2003/09/25 05:00
CRDT- 2003/03/11 04:00
PHST- 2003/03/11 04:00 [pubmed]
PHST- 2003/09/25 05:00 [medline]
PHST- 2003/03/11 04:00 [entrez]
AID - 10.1507/endocrj.49.635 [doi]
PST - ppublish
SO  - Endocr J. 2002 Dec;49(6):635-40. doi: 10.1507/endocrj.49.635.