PMID- 12634099
OWN - NLM
STAT- MEDLINE
DCOM- 20030821
LR  - 20190901
IS  - 0021-9975 (Print)
IS  - 0021-9975 (Linking)
VI  - 128
IP  - 2-3
DP  - 2003 Feb-Apr
TI  - Cerebral primitive neuroectodermal tumour in a heifer.
PG  - 195-8
AB  - A primitive neuroectodermal tumour (PNET) replacing the thalamus was discovered 
      in an 18-month-old Prim'Holstein heifer. Microscopical examination of the tumour 
      showed large sheets of densely packed cells with occasional Homer-Wright and 
      perivascular rosettes. Neoplastic cells were small with ill-defined borders, 
      scant cytoplasm and ovoid, irregularly shaped nuclei. Immunolabelling was 
      positive for vimentin and neuron-specific enolase, in agreement with previous 
      reports of PNETs in human beings and animals. This appears to be the first report 
      of cerebral PNET in cattle.
FAU - Lucas, M-N
AU  - Lucas MN
AD  - Unite d'Anatomie Pathologique, Ecole Nationale Veterinaire de Nantes, Atlanpole, 
      La Chantrerie, BP 40706 F-44307, Nantes cedex 03, France.
FAU - Nguyen, F
AU  - Nguyen F
FAU - Abadie, J
AU  - Abadie J
FAU - Kane, Y
AU  - Kane Y
FAU - Cuilliere, P
AU  - Cuilliere P
FAU - Wyers, M
AU  - Wyers M
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - J Comp Pathol
JT  - Journal of comparative pathology
JID - 0102444
RN  - 0 (Biomarkers, Tumor)
RN  - 0 (Vimentin)
RN  - EC 4.2.1.11 (Phosphopyruvate Hydratase)
SB  - IM
MH  - Animals
MH  - Biomarkers, Tumor/analysis
MH  - Brain Neoplasms/chemistry/pathology/*veterinary
MH  - Cattle
MH  - Cattle Diseases/*pathology
MH  - Fatal Outcome
MH  - Female
MH  - Immunoenzyme Techniques/veterinary
MH  - Neuroectodermal Tumors/chemistry/pathology/*veterinary
MH  - Phosphopyruvate Hydratase/analysis
MH  - Thalamus/chemistry/*pathology
MH  - Vimentin/analysis
EDAT- 2003/03/14 04:00
MHDA- 2003/08/22 05:00
CRDT- 2003/03/14 04:00
PHST- 2003/03/14 04:00 [pubmed]
PHST- 2003/08/22 05:00 [medline]
PHST- 2003/03/14 04:00 [entrez]
AID - S0021997502906110 [pii]
AID - 10.1053/jcpa.2002.0611 [doi]
PST - ppublish
SO  - J Comp Pathol. 2003 Feb-Apr;128(2-3):195-8. doi: 10.1053/jcpa.2002.0611.