PMID- 12661413
OWN - NLM
STAT- MEDLINE
DCOM- 20030813
LR  - 20181130
IS  - 0032-5449 (Print)
IS  - 0032-5449 (Linking)
VI  - 56 Suppl
DP  - 2002
TI  - [The role of immunoglobulin preparations in treatment of allergic diseases].
PG  - 41-7
AB  - Intravenous immunoglobulin (IVIG) has been used for many years to treat patients 
      with primary immunodeficiencies. More recently, IVIG has been shown to have 
      antiinflammatory activity when used at substantially higher concentrations. A 
      number of studies have examined the efficacy of IVIG in allergic diseases. For 
      patients with severe refractory asthma, sinusitis, atopic dermatitis, and 
      urticaria, IVIG offers an alternative therapy with relatively few side effects. 
      Although the mechanism by which IVIG may attenuate the allergic response is still 
      undetermined, clinical studies have shown that immunoglobulin therapy can 
      decrease serum IgE levels and increase glucocorticoid binding affinity, while in 
      vitro studies have shown that IVIG can decrease T-cell secretion of TH2 
      cytokines.
FAU - Boznanski, Andrzej
AU  - Boznanski A
AD  - I Katedra Pediatrii i Klinika Alergologii oraz Kardiologii Dzieciecej Akademii 
      Medycznej we Wroclawiu. aboz@pedalergol.am.wroc.pl
FAU - Widerska, Alicja
AU  - Widerska A
LA  - pol
PT  - Journal Article
PT  - Review
TT  - Rola preparatow immunoglobulin w leczeniu chorob alergicznych.
PL  - Poland
TA  - Postepy Hig Med Dosw
JT  - Postepy higieny i medycyny doswiadczalnej
JID - 0421052
RN  - 0 (Glucocorticoids)
RN  - 0 (Immunoglobulins, Intravenous)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Asthma/drug therapy
MH  - Glucocorticoids/metabolism
MH  - Humans
MH  - Hypersensitivity/*drug therapy/metabolism
MH  - Immunoglobulin E/blood
MH  - Immunoglobulins, Intravenous/*therapeutic use
MH  - T-Lymphocytes/metabolism
RF  - 25
EDAT- 2003/03/29 05:00
MHDA- 2003/08/14 05:00
CRDT- 2003/03/29 05:00
PHST- 2003/03/29 05:00 [pubmed]
PHST- 2003/08/14 05:00 [medline]
PHST- 2003/03/29 05:00 [entrez]
PST - ppublish
SO  - Postepy Hig Med Dosw. 2002;56 Suppl:41-7.