PMID- 12684559 OWN - NLM STAT- MEDLINE DCOM- 20030521 LR - 20220321 IS - 0736-0258 (Print) IS - 0736-0258 (Linking) VI - 20 IP - 1 DP - 2003 Feb TI - Intracortical inhibition and facilitation in paired-pulse transcranial magnetic stimulation: effect of conditioning stimulus intensity on sizes and latencies of motor evoked potentials. PG - 54-8 AB - The influence of the intensity of the conditioning stimulus on intracortical inhibition (ICI) and intracortical facilitation (ICF) was assessed in a study using paired-pulse transcranial magnetic stimulation. Interstimulus intervals (ISIs) between conditioning and test stimuli were 3 msec and 13 msec. Latencies and areas of motor evoked potentials in response to the test stimulus were measured in the right extensor carpi radialis muscle. Motor evoked potential areas with ISIs of 3 msec and 13 msec showed a different dependence on the intensity of the conditioning stimulus. In contrast, the changes of motor evoked potential latencies were fairly similar with both ISIs. The findings point to a parallel action of ICI and ICF. Furthermore, the latencies seem to be a more sensitive indicator for ICF action than the size parameters of motor evoked potentials. FAU - Kossev, Andon R AU - Kossev AR AD - Institute of Biophysics, Bulgarian Academy of Sciences, Sofia, Bulgaria. FAU - Siggelkow, Sabine AU - Siggelkow S FAU - Dengler, Reinhard AU - Dengler R FAU - Rollnik, Jens D AU - Rollnik JD LA - eng PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Clin Neurophysiol JT - Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society JID - 8506708 SB - IM MH - Action Potentials/physiology MH - Adaptation, Physiological/*physiology MH - Adult MH - Electric Stimulation/*methods MH - Electromyography MH - Evoked Potentials, Motor/*physiology MH - Female MH - Forearm/physiology MH - Humans MH - Male MH - Middle Aged MH - Motor Cortex/*physiology MH - Muscle, Skeletal/*physiology MH - Neural Inhibition/physiology MH - Reaction Time/*physiology MH - Reproducibility of Results MH - Sensitivity and Specificity MH - *Transcranial Magnetic Stimulation EDAT- 2003/04/10 05:00 MHDA- 2003/05/22 05:00 CRDT- 2003/04/10 05:00 PHST- 2003/04/10 05:00 [pubmed] PHST- 2003/05/22 05:00 [medline] PHST- 2003/04/10 05:00 [entrez] AID - 10.1097/00004691-200302000-00007 [doi] PST - ppublish SO - J Clin Neurophysiol. 2003 Feb;20(1):54-8. doi: 10.1097/00004691-200302000-00007.