PMID- 12688094 OWN - NLM STAT- MEDLINE DCOM- 20030501 LR - 20181130 IS - 1025-9589 (Print) IS - 1025-9589 (Linking) VI - 14 IP - 4 DP - 2002 Oct-Dec TI - Tuberculosis control: current status, challenges and barriers ahead in 22 high endemic countries. PG - 11-5 AB - BACKGROUND: Despite the fact that Directly Observed Treatment Strategy (DOTS) short course is cost effective and universally recommended by WHO for effective TB control, it is beyond the financial reach of several highly endemic countries. This article aims at identifying barriers in DOTS's implementation and progress in 22 high burden countries (HBCs) from TB. METHODS: Medline abstracts, published papers and WHO reports were retrieved, critically examined and compared keeping standard parameters of TB control in view. RESULTS & CONCLUSION: The increasing caseload, morbidity and mortality due to TB in high burden countries have become a major health challenge and threat to the health systems. The escalated burden of disease and deaths due to TB has posed a great threat to the international security. In the last decade little progress has been witnessed in the implementation of WHO's recommended strategy called DOTS in the 22 high burden countries. Afghanistan, Pakistan, India, Brazil, Zimbabwe, S. Africa and Uganda are some of the countries still facing challenges in the effective introduction, implementation and expansion of DOTS. Financial inabilities contribute greatly to the failure of respective national TB control programs. High burden countries are usually in the economic recession or passing through severe socio-political turmoil that has further reduced spending on TB control. Majority depends on the international assistance and put little domestic efforts. Coupled with the lack of political commitment to the issue of TB control, authors urge high TB control Program managers in HBCs to increase spending and pay a great deal of commitment to the universal implementation of DOTS, increase case detection and case management to attain their global targets. FAU - Ibrahim, Khan M AU - Ibrahim KM AD - Section of International Public Health (S-IPH), University of Bielefeld, Germany. ibrahim.khan@uni-bielefeld.de FAU - Khan, Samreen AU - Khan S FAU - Laaser, Ulrich AU - Laaser U LA - eng PT - Journal Article PL - Pakistan TA - J Ayub Med Coll Abbottabad JT - Journal of Ayub Medical College, Abbottabad : JAMC JID - 8910750 SB - IM MH - *Developing Countries MH - Directly Observed Therapy/economics/*statistics & numerical data MH - Endemic Diseases/economics/prevention & control/*statistics & numerical data MH - Humans MH - Tuberculosis/economics/*epidemiology/*prevention & control EDAT- 2003/04/12 05:00 MHDA- 2003/05/02 05:00 CRDT- 2003/04/12 05:00 PHST- 2003/04/12 05:00 [pubmed] PHST- 2003/05/02 05:00 [medline] PHST- 2003/04/12 05:00 [entrez] PST - ppublish SO - J Ayub Med Coll Abbottabad. 2002 Oct-Dec;14(4):11-5.