PMID- 12695145
OWN - NLM
STAT- MEDLINE
DCOM- 20030731
LR  - 20131121
IS  - 1167-1122 (Print)
IS  - 1167-1122 (Linking)
VI  - 13
IP  - 2
DP  - 2003 Mar-Apr
TI  - Nitrendipine-induced subacute cutaneous lupus erythematosus.
PG  - 213-6
AB  - A 66-year-old man presented with widespread annular and bullous subacute 
      cutaneous lupus erythematosus (SCLE), developed after starting treatment for 
      hypertension with the calcium channel blocker nitrendipine. A few days after 
      withdrawal of the drug, while cutaneous manifestations were improving, left 
      hemiparesis occurred. Laboratory investigations showed, in addition to anti-Ro, 
      anti-La and anti-histone antibodies, the presence of lupus anticoagulant, 
      anticardiolipin antibodies, prolonged APTT and thrombocytopenia. On the basis of 
      the spontaneous regression of the patient's skin lesions after discontinuation of 
      the drug, a possible relationship between nitrendipine intake, the clinical 
      events and the biological findings is discussed.
FAU - Marzano, Angelo V
AU  - Marzano AV
AD  - Institute of Dermatological Sciences of the University of Milan, Via Pace, Italy. 
      mizzidoc@libero.it
FAU - Borghi, Alessandro
AU  - Borghi A
FAU - Mercogliano, Maurizio
AU  - Mercogliano M
FAU - Facchetti, Maura
AU  - Facchetti M
FAU - Caputo, Ruggero
AU  - Caputo R
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - France
TA  - Eur J Dermatol
JT  - European journal of dermatology : EJD
JID - 9206420
RN  - 0 (Autoantibodies)
RN  - 0 (Calcium Channel Blockers)
RN  - 9B627AW319 (Nitrendipine)
SB  - IM
MH  - Aged
MH  - Autoantibodies/*immunology
MH  - Calcium Channel Blockers/*adverse effects
MH  - Humans
MH  - Lupus Erythematosus, Cutaneous/*chemically induced/*immunology
MH  - Male
MH  - Nitrendipine/*adverse effects
MH  - Paresis/chemically induced
EDAT- 2003/04/16 05:00
MHDA- 2003/08/02 05:00
CRDT- 2003/04/16 05:00
PHST- 2003/04/16 05:00 [pubmed]
PHST- 2003/08/02 05:00 [medline]
PHST- 2003/04/16 05:00 [entrez]
PST - ppublish
SO  - Eur J Dermatol. 2003 Mar-Apr;13(2):213-6.