PMID- 12702180 OWN - NLM STAT- MEDLINE DCOM- 20030515 LR - 20221207 IS - 0041-1132 (Print) IS - 0041-1132 (Linking) VI - 43 IP - 5 DP - 2003 May TI - Adverse effects in blood donors after whole-blood donation: a study of 1000 blood donors interviewed 3 weeks after whole-blood donation. PG - 598-603 AB - BACKGROUND: There are no reports in the transfusion medicine literature that describe adverse reactions and donor arm injuries after whole-blood donation based on solicited information. STUDY DESIGN AND METHODS: The present study solicited adverse reaction and donor arm injury information from 1000 randomly selected whole-blood donors approximately 3 weeks after the whole-blood donation. Two 16-gauge phlebotomy needles in use were also compared. RESULTS: Thirty-six percent of the donors had one or more adverse effects (AEs). The most common systemic AEs were fatigue (7.8%), vasovagal symptoms (5.3%), and nausea and vomiting (1.1%). The most common arm findings were bruise (22.7%), arm soreness (10.0%), and hematoma (1.7%). Men were half as likely as women to have an AE (23% AE vs. 48% AE, p < 0.0001). Repeat blood donors had fewer AEs than first-time blood donors (36% AE vs. 47% AE, p < 0.007), and African-American donors had numbers of AEs similar to those of Caucasian donors (31% AE vs. 38% AE, p = 0.30). The two phlebotomy needles did not differ in causing blood donor AEs. CONCLUSION: AEs after donation and complaints may be more common than previously thought. The postdonation interview is a good tool for defining the blood donor's experience. It can also be used to evaluate and potentially improve blood donor safety and comfort. FAU - Newman, Bruce H AU - Newman BH AD - American Red Cross Blood Services, SE Michigan Region, 100 Mack, Detroit, MI 48201, USA. newmanb@usa.redcross.org FAU - Pichette, Shawn AU - Pichette S FAU - Pichette, Dena AU - Pichette D FAU - Dzaka, Ema AU - Dzaka E LA - eng PT - Journal Article PL - United States TA - Transfusion JT - Transfusion JID - 0417360 SB - IM CIN - Transfusion. 2004 Jan;44(1):135-6; author reply 136. PMID: 14692981 MH - Adult MH - Black or African American MH - Arm MH - Arm Injuries/etiology MH - Black People MH - *Blood Donors MH - Contusions/etiology MH - Fatigue/etiology MH - Female MH - Gastrointestinal Diseases/etiology MH - Hematoma/etiology MH - Humans MH - Interviews as Topic MH - Male MH - Needles/adverse effects MH - Pain/etiology MH - White People EDAT- 2003/04/19 05:00 MHDA- 2003/05/16 05:00 CRDT- 2003/04/19 05:00 PHST- 2003/04/19 05:00 [pubmed] PHST- 2003/05/16 05:00 [medline] PHST- 2003/04/19 05:00 [entrez] AID - 368 [pii] AID - 10.1046/j.1537-2995.2003.00368.x [doi] PST - ppublish SO - Transfusion. 2003 May;43(5):598-603. doi: 10.1046/j.1537-2995.2003.00368.x.