PMID- 12708981 OWN - NLM STAT- MEDLINE DCOM- 20030902 LR - 20190823 IS - 0105-4538 (Print) IS - 0105-4538 (Linking) VI - 58 IP - 4 DP - 2003 Apr TI - Allergy to millet: another risk for atopic bird keepers. PG - 325-8 AB - BACKGROUND: Millet has been reported to induce not very frequent but severe anaphylactic reactions following ingestion. Seven individuals who all kept cage birds experienced allergic reactions after ingestion of millet-containing food. METHODS: We investigated the immunoglobulin E (IgE)-reactivity of these individuals to millet employing immunoblotting, RAST and skin prick tests. As the sensitization possibly occurred via the inhalant route we investigated millet-specific IgE levels of 16 additional sera from bird keepers with proven atopy, in retrospect. RESULTS: All patients who had experienced reactions after ingestion of millet displayed millet-specific IgE. Sixty-three percent of the atopic bird keepers possessed millet-specific IgE. By means of immunoblotting three major allergens in millet extract were detected. CONCLUSIONS: Our results indicate that millet plays an important role as inhalant allergen for atopic bird keepers. A sensitization to millet may subsequently also elicit food allergy. FAU - Bohle, B AU - Bohle B AD - Department of Pathophysiology, University of Vienna, Vienna, Austria. FAU - Hirt, W AU - Hirt W FAU - Nachbargauer, P AU - Nachbargauer P FAU - Ebner, H AU - Ebner H FAU - Ebner, C AU - Ebner C LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Denmark TA - Allergy JT - Allergy JID - 7804028 RN - 0 (Allergens) RN - 0 (Dust) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adolescent MH - Adult MH - Allergens/adverse effects/*immunology MH - Anaphylaxis/*etiology MH - Animal Feed/*adverse effects MH - Animals MH - Birds MH - Child MH - Dust MH - Female MH - Humans MH - Hypersensitivity, Immediate/*etiology MH - Immunoblotting MH - Immunoglobulin E/*blood MH - Male MH - Middle Aged MH - Panicum/adverse effects/*immunology MH - Radioallergosorbent Test MH - Retrospective Studies MH - Skin Tests EDAT- 2003/04/24 05:00 MHDA- 2003/09/03 05:00 CRDT- 2003/04/24 05:00 PHST- 2003/04/24 05:00 [pubmed] PHST- 2003/09/03 05:00 [medline] PHST- 2003/04/24 05:00 [entrez] AID - 101 [pii] AID - 10.1034/j.1398-9995.2003.00101.x [doi] PST - ppublish SO - Allergy. 2003 Apr;58(4):325-8. doi: 10.1034/j.1398-9995.2003.00101.x.