PMID- 12713203 OWN - NLM STAT- MEDLINE DCOM- 20030820 LR - 20190901 IS - 0096-882X (Print) IS - 0096-882X (Linking) VI - 64 IP - 2 DP - 2003 Mar TI - Changes in drinking status, serious illness and mortality. PG - 278-85 AB - OBJECTIVE: We studied the relationship of drinking and abstaining with all-cause mortality in a two-measurement-point prospective study to assess the importance of drinking change versus stability among the healthy and seriously ill. METHOD: The National Health and Nutrition Examination Survey I (NHANES I) and follow-up of men and women (age 22-49 and 50+) at first measurement (1971-74) who survived until second measurement (1982-84) were followed in death records for 10 years (1993). Cox proportional hazards models evaluated those with and without serious illness. RESULTS: We found no elevated mortality risk for consistent never drinkers, but consistent heavier drinkers were at higher all-cause risk among men. Groups of abstainers significantly differed for mortality risk, and illness was implicated in these differences. New drinkers who formerly abstained did not improve their chances for longevity. Heavier drinking men who decreased consumption increased their chances for survival. CONCLUSIONS: Abstinence per se is not a risk factor for all-cause mortality, but heavier drinking is a risk factor among men. Adoption of drinking among former abstainers does not improve chances for survival. Reduction in consumption among heavier drinking men improves chances for survival. FAU - Fillmore, Kaye Middleton AU - Fillmore KM AD - Department of Social and Behavioral Science, University of California, San Francisco, Box 0612, San Francisco, California 94143-0612, USA. kmfalc@itsa.ucsf.edu FAU - Kerr, William C AU - Kerr WC FAU - Bostrom, Alan AU - Bostrom A LA - eng GR - K01 AA00073/AA/NIAAA NIH HHS/United States GR - R01 AA07034/AA/NIAAA NIH HHS/United States PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - J Stud Alcohol JT - Journal of studies on alcohol JID - 7503813 SB - IM MH - Adult MH - Aged MH - Alcohol Drinking/*epidemiology/mortality MH - Chronic Disease/*epidemiology/mortality MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - Temperance/statistics & numerical data MH - United States/epidemiology EDAT- 2003/04/26 05:00 MHDA- 2003/08/21 05:00 CRDT- 2003/04/26 05:00 PHST- 2003/04/26 05:00 [pubmed] PHST- 2003/08/21 05:00 [medline] PHST- 2003/04/26 05:00 [entrez] AID - 10.15288/jsa.2003.64.278 [doi] PST - ppublish SO - J Stud Alcohol. 2003 Mar;64(2):278-85. doi: 10.15288/jsa.2003.64.278.