PMID- 12730648
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 2532-8689 (Electronic)
IS  - 1124-9390 (Linking)
VI  - 6
IP  - 4
DP  - 1998
TI  - [CD30 (ki-1) antigen expression in acute infectious mononucleosis].
PG  - 228-232
AB  - The activation antigen CD30 (Ki-1) which is expressed by the lymphocytes T and B 
      is related to the "nerve growth factor" (NFGR) like the receptor of the "tumor 
      necrosis factor" (TNF) and is expressed in the group of large-cell anaplastic 
      lymphoma (ACLC) and Hodgkin's lymphoma and in non-Hodgkin's lymphoma and within 
      the T cells of infectious Mononucleosis. We describe a case of a 18 year-old who 
      contracted Acute Infectious Mononucleosis showing lateral cervical lympho 
      adenopathy. The histologic examination was suggestive for a large-cell anaplastic 
      lymphoma with the antigen CD30, expressed by severa atypical immunoblasts. The 
      remarkable immunoblastic proliferation with Reed-Sternberg-like cells, in milieu 
      polymorphous inflammatory cells present in the course of Infectious 
      Mononucleosis, can simulate large cell anaplastic lymphoma, as well as Hodgkins 
      disease and non-Hodgkins lymphoma. The diagnosis for Infectious Mononucleosis is 
      usually clinical and serological but in cases of cervical lymphnode biopsy a 
      differential diagnosis must be done with positive lymphoma CD30. The criteria to 
      differentiate histologically the Infectious Mononucleosis with large cell 
      anaplastic lymphoma and non-Hodgkin s lymphoma are discussed. Finally, the 
      relationship between Infectious Mononucleosis and lymphoproliferative disease 
      Epstein-Barr virus related is examined.
FAU - Bellissima, P
AU  - Bellissima P
AD  - Istituto di Patologia Generale dell'Universita degli Studi di Catania, Italy.
FAU - Tricoli, D
AU  - Tricoli D
FAU - Platania, S
AU  - Platania S
LA  - ita
PT  - Journal Article
TT  - L'espresione dell'antigene CD30 (K1-1) nella mononucleosi infettova acuta.
PL  - Italy
TA  - Infez Med
JT  - Le infezioni in medicina
JID - 9613961
EDAT- 2003/05/06 05:00
MHDA- 2003/05/06 05:01
CRDT- 2003/05/06 05:00
PHST- 2003/05/06 05:00 [pubmed]
PHST- 2003/05/06 05:01 [medline]
PHST- 2003/05/06 05:00 [entrez]
PST - ppublish
SO  - Infez Med. 1998;6(4):228-232.