PMID- 12739372
OWN - NLM
STAT- MEDLINE
DCOM- 20030620
LR  - 20201208
IS  - 0387-5911 (Print)
IS  - 0387-5911 (Linking)
VI  - 77
IP  - 4
DP  - 2003 Apr
TI  - [Increasing drug resistance in Vibrio cholerae O1 and non-O1 strains isolated 
      from diarrheal cases in Japan].
PG  - 195-202
AB  - Drug resistance trends were investigated for 271 Vibrio cholerae O1 (V.c O1) and 
      401 V. cholerae non-O1 (V.c non-O1) strains isolated from mainly imported 
      diarrheal cases during 1981-2001 in Japan. The results of drug resistance test 
      using 8 drugs (CP, TC, SM, KM, ABPC, ST, NA, and NFLX) showed that 34.7% of the 
      V. c O1 strains and 15.7% of V.c non-O1 strains were multi-drug or mono-drug 
      resistant. The incidence of drug resistant strains has increased since 1991, and 
      it has been remarkable in V.c O1 strains that increased from 1.2% in 1981-1985 to 
      70.8% in 1996-2001. The drug resistance patterns of the resistant strains 
      classified into 6 types in V.c O1 and 21 types in V.c non-O1. The prevalent 
      patterns recognized were SM (75.5%), CP.TC.SM.ST (10.6%) and CP.SM.ST (8.5%) in 
      V.c O1, and SM (25.4%) and ABPC (25.4%) in V.c non-O1. Ten V.c O1 strains (3.7%) 
      and 10 V.c non-O1 strains (2.5%) were multi-drug resistant including TC. Among 
      those, 13 strains were isolated from travelers who returned to Japan from 
      Thailand. One V.c O1 strain (0.4%) and 6 V.c non-O1 strains (1.5%) were NA 
      high-resistant and fluoroquinolones low-sensitive. Among those, 4 strains were 
      isolated from travelers who returned to Japan from India.
FAU - Matsushita, Shigeru
AU  - Matsushita S
AD  - Tokyo Metropolitan Research Laboratory of Public Health.
FAU - Kawamura, Maho
AU  - Kawamura M
FAU - Konishi, Noriko
AU  - Konishi N
FAU - Kai, Akemi
AU  - Kai A
FAU - Katoh, Rei
AU  - Katoh R
FAU - Ogata, Kazue
AU  - Ogata K
FAU - Itoh, Tadahiko
AU  - Itoh T
FAU - Yano, Kazuyoshi
AU  - Yano K
FAU - Morita, Koji
AU  - Morita K
FAU - Watanabe, Noboru
AU  - Watanabe N
FAU - Kanamori, Masato
AU  - Kanamori M
FAU - Kudoh, Yasuo
AU  - Kudoh Y
LA  - jpn
PT  - Journal Article
PL  - Japan
TA  - Kansenshogaku Zasshi
JT  - Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious 
      Diseases
JID - 0236671
RN  - 0 (Fluoroquinolones)
RN  - F8VB5M810T (Tetracycline)
SB  - IM
MH  - Diarrhea/*microbiology
MH  - Drug Resistance, Bacterial
MH  - Fluoroquinolones/*pharmacology
MH  - Humans
MH  - Tetracycline/*pharmacology
MH  - *Tetracycline Resistance
MH  - Travel
MH  - Vibrio cholerae/*drug effects/isolation & purification
MH  - Vibrio cholerae O1/*drug effects/isolation & purification
EDAT- 2003/05/13 05:00
MHDA- 2003/06/21 05:00
CRDT- 2003/05/13 05:00
PHST- 2003/05/13 05:00 [pubmed]
PHST- 2003/06/21 05:00 [medline]
PHST- 2003/05/13 05:00 [entrez]
AID - 10.11150/kansenshogakuzasshi1970.77.195 [doi]
PST - ppublish
SO  - Kansenshogaku Zasshi. 2003 Apr;77(4):195-202. doi: 
      10.11150/kansenshogakuzasshi1970.77.195.