PMID- 12747516
OWN - NLM
STAT- MEDLINE
DCOM- 20030610
LR  - 20221207
IS  - 0003-9896 (Print)
IS  - 0003-9896 (Linking)
VI  - 58
IP  - 1
DP  - 2003 Jan
TI  - Smoking as a determinant of high organochlorine levels in Greenland.
PG  - 30-6
AB  - The authors investigated the accumulation of organochlorines among smoking and 
      nonsmoking Inuit hunters (n = 48) in Uummanaq, Greenland, a population with high 
      dietary exposure to persistent organic pollutants (POPs). Human plasma 
      organochlorine levels were positively correlated with age, marine diet, and 
      smoking or plasma cotinine in multiple linear-regression models (p < 0.001). Body 
      mass index was inversely correlated with organochlorine accumulation, independent 
      of smoking status. These findings confirm that the source of POPs among the Inuit 
      in Greenland is diet, but smoking is an important determinant of POP 
      bioaccumulation. Smoking cessation may provide a means to lower the body burden 
      of POPs.
FAU - Deutch, Bente
AU  - Deutch B
AD  - Centre of Arctic Environmental Medicine, Aarhus University, Aarhus, Denmark. 
      bd@mil.au.dk
FAU - Pedersen, Henning Sloth
AU  - Pedersen HS
FAU - Jorgensen, Eva C Bonefeld
AU  - Jorgensen EC
FAU - Hansen, Jens C
AU  - Hansen JC
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Arch Environ Health
JT  - Archives of environmental health
JID - 0212627
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Insecticides)
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - Adult
MH  - Body Mass Index
MH  - *Diet/adverse effects
MH  - Environmental Exposure/adverse effects/analysis
MH  - Greenland/epidemiology
MH  - Health Surveys
MH  - Humans
MH  - *Hydrocarbons, Chlorinated
MH  - Insecticides/adverse effects/*blood
MH  - *Inuit
MH  - Life Style
MH  - Linear Models
MH  - Male
MH  - Pesticide Residues/adverse effects/*blood
MH  - Seafood/adverse effects/*analysis
MH  - Smoking/*epidemiology
EDAT- 2003/05/16 05:00
MHDA- 2003/06/11 05:00
CRDT- 2003/05/16 05:00
PHST- 2003/05/16 05:00 [pubmed]
PHST- 2003/06/11 05:00 [medline]
PHST- 2003/05/16 05:00 [entrez]
AID - 10.3200/AEOH.58.1.30-36 [doi]
PST - ppublish
SO  - Arch Environ Health. 2003 Jan;58(1):30-6. doi: 10.3200/AEOH.58.1.30-36.