PMID- 12755850
OWN - NLM
STAT- MEDLINE
DCOM- 20031003
LR  - 20220410
IS  - 0065-1591 (Print)
IS  - 0065-1591 (Linking)
IP  - 416
DP  - 2003
TI  - The Clinical Global Impression-Schizophrenia scale: a simple instrument to 
      measure the diversity of symptoms present in schizophrenia.
PG  - 16-23
AB  - OBJECTIVE: To describe the development and validation of the Clinical Global 
      Impression-Schizophrenia (CGI-SCH) scale, designed to assess positive, negative, 
      depressive and cognitive symptoms in schizophrenia. METHOD: The CGI-SCH scale was 
      adapted from the CGI scale. Concurrent validity and sensitivity to change were 
      assessed by comparison with the Positive and Negative Symptom Severity (PANSS) 
      and Global Assessment of Functioning (GAF) scales. To evaluate inter-rater 
      reliability, all patients were assessed by two clinicians. RESULTS: Symptoms were 
      assessed in 114 patients. Correlation coefficients between the CGI-SCH and the 
      GAF and PANSS scores were high (most above 0.75), and were highest for positive 
      and negative symptoms. Reliability was substantial (intraclass correlation 
      coefficient, ICC > 0.70) in all but one dimension (depressive dimension, ICC = 
      0.64). CONCLUSION: The CGI-SCH scale is a valid, reliable instrument to evaluate 
      severity and treatment response in schizophrenia. Given its simplicity, brevity 
      and clinical face validity, the scale is appropriate for use in observational 
      studies and routine clinical practice.
FAU - Haro, J M
AU  - Haro JM
AD  - Research and Development Unit, Sant Joan de Deu-SSM, Sant Boi, Barcelona, Spain. 
      27652jha@comb.es
FAU - Kamath, S A
AU  - Kamath SA
FAU - Ochoa, S
AU  - Ochoa S
FAU - Novick, D
AU  - Novick D
FAU - Rele, K
AU  - Rele K
FAU - Fargas, A
AU  - Fargas A
FAU - Rodriguez, M J
AU  - Rodriguez MJ
FAU - Rele, R
AU  - Rele R
FAU - Orta, J
AU  - Orta J
FAU - Kharbeng, A
AU  - Kharbeng A
FAU - Araya, S
AU  - Araya S
FAU - Gervin, M
AU  - Gervin M
FAU - Alonso, J
AU  - Alonso J
FAU - Mavreas, V
AU  - Mavreas V
FAU - Lavrentzou, E
AU  - Lavrentzou E
FAU - Liontos, N
AU  - Liontos N
FAU - Gregor, K
AU  - Gregor K
FAU - Jones, P B
AU  - Jones PB
CN  - SOHO Study Group
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Denmark
TA  - Acta Psychiatr Scand Suppl
JT  - Acta psychiatrica Scandinavica. Supplementum
JID - 0370365
SB  - IM
MH  - Adult
MH  - Cognition Disorders/physiopathology
MH  - Depression/physiopathology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multicenter Studies as Topic
MH  - Observer Variation
MH  - *Psychiatric Status Rating Scales
MH  - Reproducibility of Results
MH  - Schizophrenia/*physiopathology
MH  - Schizophrenic Psychology
MH  - Sensitivity and Specificity
MH  - Severity of Illness Index
MH  - Treatment Outcome
EDAT- 2003/05/21 05:00
MHDA- 2003/10/04 05:00
CRDT- 2003/05/21 05:00
PHST- 2003/05/21 05:00 [pubmed]
PHST- 2003/10/04 05:00 [medline]
PHST- 2003/05/21 05:00 [entrez]
AID - 98 [pii]
AID - 10.1034/j.1600-0447.107.s416.5.x [doi]
PST - ppublish
SO  - Acta Psychiatr Scand Suppl. 2003;(416):16-23. doi: 
      10.1034/j.1600-0447.107.s416.5.x.