PMID- 12760266
OWN - NLM
STAT- MEDLINE
DCOM- 20030612
LR  - 20190607
IS  - 1226-3303 (Print)
IS  - 2005-6648 (Electronic)
IS  - 1226-3303 (Linking)
VI  - 18
IP  - 1
DP  - 2003 Mar
TI  - The role of cardiopulmonary exercise test in mitral and aortic regurgitation: it 
      can predict post-operative results.
PG  - 35-9
AB  - BACKGROUND: We evaluated the efficacy of the cardiopulmonary exercise test as an 
      objective indicator of functional status and as a pre-operative prognostic 
      indicator in patients with mitral regurgitation (MR) and aortic regurgitation 
      (AR). METHODS: Cardiopulmonary exercise tests and echocardiography were performed 
      in 47 patients (MR: 30, AR: 15, MR + AR: 2) before surgery and repeated one year 
      after surgery. We compared the New York Heart Association (NYHA) functional 
      class, peak oxygen consumption rate (VO2peak), exercise duration, left 
      ventricular dimension and ejection fraction, before and after surgery. RESULTS: 
      Initial VO2peak and exercise duration were significantly different according to 
      NYHA class. A year later, NYHA functional class improved from 2.1 +/- 0.1 to 1.4 
      +/- 0.1 (p < 0.001). The VO2peak was significantly increased (21.7 +/- 1.0 to 
      23.7 +/- 1.0 mL/kg per min, p = 0.008) and exercise duration also increased 
      (521.7 +/- 35.9 to 623.3 +/- 35.7 seconds, p < 0.001). When patients were 
      analysed according to their post-operative NYHA functional class, those with 
      class I showed significantly different pre-operative VO2peak (class I: 23.7 +/- 
      1.1, II: 18.3 +/- 1.5 mL/kg per min, p = 0.005) and exercise durations (class I: 
      587.5 +/- 43.2, II: 415.6 +/- 55.7 seconds, p = 0.02). Patients with higher 
      pre-operative VO2peak (19.0 mL/kg per min) more frequently became NYHA functional 
      class I than those with a lower pre-operative VO2peak (76.7% vs. 35.3%, p = 
      0.02). But baseline left ventricular dimension and ejection fraction by 
      echocardiography were not different between post-operative class I and II group. 
      CONCLUSION: VO2peak and exercise duration are excellent parameters to evaluate 
      the subjective functional class and to predict the post-operative functional 
      class of patients with MR and/or AR. Patients with a pre-operative VO2peak of 
      19.0 mL/kg per min or more will have a better functional status one year after 
      surgery.
FAU - Kim, Hyun Joong
AU  - Kim HJ
AD  - Division of Cardiovascular Medicine, Samsung Medical Center, Sungkyunkwan 
      University School of Medicine, 50 Ilwon-dong, Kangnam-ku, Seoul 135-170, Korea. 
      kphong@smc.samsung.co.kr
FAU - Park, Seung Woo
AU  - Park SW
FAU - Cho, Byung Ryul
AU  - Cho BR
FAU - Hong, Sun Hee
AU  - Hong SH
FAU - Park, Pyo Won
AU  - Park PW
FAU - Hong, Kyung Pyo
AU  - Hong KP
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Korea (South)
TA  - Korean J Intern Med
JT  - The Korean journal of internal medicine
JID - 8712418
SB  - IM
MH  - Adult
MH  - Aortic Valve Insufficiency/diagnosis/*surgery
MH  - Chi-Square Distribution
MH  - Cohort Studies
MH  - Exercise Test
MH  - Exercise Tolerance
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Valve Prosthesis Implantation/*methods
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve Insufficiency/diagnosis/*surgery
MH  - Oxygen Consumption
MH  - Postoperative Period
MH  - Preoperative Care
MH  - Probability
MH  - Prospective Studies
MH  - Pulmonary Gas Exchange
MH  - Severity of Illness Index
MH  - Statistics, Nonparametric
MH  - Stroke Volume
MH  - Treatment Outcome
PMC - PMC4531601
EDAT- 2003/05/23 05:00
MHDA- 2003/06/13 05:00
PMCR- 2003/03/01
CRDT- 2003/05/23 05:00
PHST- 2003/05/23 05:00 [pubmed]
PHST- 2003/06/13 05:00 [medline]
PHST- 2003/05/23 05:00 [entrez]
PHST- 2003/03/01 00:00 [pmc-release]
AID - kjim-18-1-35-6 [pii]
AID - 10.3904/kjim.2003.18.1.35 [doi]
PST - ppublish
SO  - Korean J Intern Med. 2003 Mar;18(1):35-9. doi: 10.3904/kjim.2003.18.1.35.