PMID- 12767546 OWN - NLM STAT- MEDLINE DCOM- 20031030 LR - 20190816 IS - 0167-5273 (Print) IS - 0167-5273 (Linking) VI - 89 IP - 2-3 DP - 2003 Jun TI - Long-term results after partial left ventriculectomy. PG - 223-30 AB - BACKGROUND: Long-term clinical, echocardiographic and hemodynamic effects after partial left ventriculectomy (PLV) and predictors of outcome have been determined. METHODS: Between January 1995 and July 1999, PLV was performed in 39 patients. In 15 patients the etiology of heart failure was idiopathic dilated cardiomyopathy (DCMP), 19 patients had ischemic cardiomyopathy (ICMP) and five patients had valvular cardiomyopathy. Concomitant procedures included coronary artery bypass grafting in 16 patients, mitral valve repair in 33 patients and aortic valve replacement in five patients. All patients belonged in New York Heart Association (NYHA) functional class III or IV. Mean follow-up was 663+/-514 days. Clinical, echocardiographic and hemodynamic assessments and metabolic stress testing were performed preoperatively, within 30 days postoperatively and 6, 12 and 24 months after the operation. RESULTS: Actuarial survival was 64% after 1 year, 55% after 2 years and 44% 3 years after the operation. In patients with ICMP as well as in patients with DCMP actuarial 1 year survival was 60%. At 2-year follow-up NYHA functional class was improved significantly (P<0.05), but LV ejection fraction, LV end-diastolic diameter, cardiac index and peak oxygen consumption did not differ significantly from preoperative values. Analysis of factors influencing postoperative outcome indicated that decreased left ventricular wall thickness and a failure to increase the stroke volume index as a response to preoperative dobutamine administration were associated with postoperative mortality. CONCLUSIONS: PLV is associated with considerable postoperative mortality and lacking long-term improvement of cardiac performance. FAU - Claus, Matthias AU - Claus M AD - Klinik fur Innere Medizin mit Schwerpunkt Kardiologie, Angiologie und Pulmologie, Universitatsklinikum Charite, Campus Mitte, Humboldt-Universitat, Schumannstr. 20/21, D-10117, Berlin, Germany. matthias.claus@charite.de FAU - Beling, Mark AU - Beling M FAU - Grohmann, Andrea AU - Grohmann A FAU - Borges, Adrian C AU - Borges AC FAU - Baumann, Gert AU - Baumann G LA - eng PT - Journal Article PL - Netherlands TA - Int J Cardiol JT - International journal of cardiology JID - 8200291 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Cardiac Surgical Procedures/*methods/*mortality MH - Female MH - Heart Failure/diagnosis/mortality/*physiopathology/*surgery MH - Heart Ventricles/physiopathology/*surgery MH - Hemodynamics/physiology MH - Humans MH - Male MH - Middle Aged MH - Predictive Value of Tests MH - Prospective Studies MH - Survival Analysis MH - Time Factors MH - Treatment Outcome EDAT- 2003/05/28 05:00 MHDA- 2003/10/31 05:00 CRDT- 2003/05/28 05:00 PHST- 2003/05/28 05:00 [pubmed] PHST- 2003/10/31 05:00 [medline] PHST- 2003/05/28 05:00 [entrez] AID - S016752730200503X [pii] AID - 10.1016/s0167-5273(02)00503-x [doi] PST - ppublish SO - Int J Cardiol. 2003 Jun;89(2-3):223-30. doi: 10.1016/s0167-5273(02)00503-x.