PMID- 12775359
OWN - NLM
STAT- MEDLINE
DCOM- 20040223
LR  - 20181113
IS  - 0962-9351 (Print)
IS  - 0962-9351 (Linking)
VI  - 12
IP  - 2
DP  - 2003 Apr
TI  - Allergic diseases, drug adverse reactions and total immunoglobulin E levels in 
      lupus erythematosus patients.
PG  - 95-9
AB  - BACKGROUND: The association of allergic diseases, drug adverse reactions and 
      elevated total immunoglobulin E (IgE) concentration in systemic lupus 
      erythematosus patients remains controversial. The aim of the study was to 
      investigate the prevalence of those features in active and inactive systemic 
      lupus erythematosus patients, and in the control group as well. METHODS: Total 
      IgE concentration was evaluated by enzyme-linked immunosorbent assay. RESULTS AND 
      CONCLUSIONS: The results of our study revealed that concomitant allergic diseases 
      were not more frequent in systemic lupus erythematosus patients than in the 
      general population. Total IgE concentration was significantly higher during the 
      active stage of the disease. Drug reactions were very frequent but not connected 
      with IgE elevation. Our results indicate that IgE may play a role in lupus 
      pathogenesis, especially in the active phase of the disease.
FAU - Wozniacka, Anna
AU  - Wozniacka A
AD  - Department of Dermatology, Medical University of Lodz, Krzemieniecka 5, 94-017 
      Lodz, Poland. wozniacka@bmp.net.pl
FAU - Sysa-Jedrzejowska, Anna
AU  - Sysa-Jedrzejowska A
FAU - Robak, Ewa
AU  - Robak E
FAU - Samochocki, Zbigniew
AU  - Samochocki Z
FAU - Zak-Prelich, Malgorzata
AU  - Zak-Prelich M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Mediators Inflamm
JT  - Mediators of inflammation
JID - 9209001
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Acute Disease
MH  - Adult
MH  - Aged
MH  - Drug Hypersensitivity/*epidemiology/*immunology
MH  - Female
MH  - Humans
MH  - Hypersensitivity/*epidemiology/*immunology
MH  - Immunoglobulin E/blood
MH  - Lupus Erythematosus, Systemic/*epidemiology/*immunology
MH  - Male
MH  - Middle Aged
MH  - Prevalence
PMC - PMC1781602
EDAT- 2003/05/31 05:00
MHDA- 2004/02/24 05:00
PMCR- 2003/04/01
CRDT- 2003/05/31 05:00
PHST- 2003/05/31 05:00 [pubmed]
PHST- 2004/02/24 05:00 [medline]
PHST- 2003/05/31 05:00 [entrez]
PHST- 2003/04/01 00:00 [pmc-release]
AID - 0GJGFXKVXP6UQQXC [pii]
AID - 10.1080/0962935031000097709 [doi]
PST - ppublish
SO  - Mediators Inflamm. 2003 Apr;12(2):95-9. doi: 10.1080/0962935031000097709.