PMID- 1277925
OWN - NLM
STAT- MEDLINE
DCOM- 19760901
LR  - 20190514
IS  - 0012-3692 (Print)
IS  - 0012-3692 (Linking)
VI  - 70
IP  - 1
DP  - 1976 Jul
TI  - Quantitative levels of immunoglobulin E in advanced tuberculosis.
PG  - 21-3
AB  - Quantitative levels of immunoglobulin E (IgE) were determined in samples of sera 
      obtained from 29 patients with proven moderate to far-advanced tuberculosis. The 
      sensitive radioimmunoassay test for IgE was used. Statistical analysis of the 
      results revealed no difference in IgE values as compared to a control group of 
      normal sera. In contrast to other chronic pulmonary infections, such as 
      bronchopulmonary aspergillosis, the IgE level in pulmonary tuberculous infection 
      is of no diagnostic significance. Simultaneous determination of levels of 
      immunoglobulins G, A, M, and D (IgG, IgA, IgM, IgD) in these same sera by radial 
      immunodiffusion showed elevated IgG and lowered IgM levels in the tuberculous 
      patients, confirming previous studies. The significance of these alterations in 
      immunoglobulin levels is unclear and may represent a secondary phenomenon rather 
      than a primary host response.
FAU - Casterline, C L
AU  - Casterline CL
FAU - Evans, R 3rd
AU  - Evans R 3rd
FAU - Ward, G W Jr
AU  - Ward GW Jr
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Chest
JT  - Chest
JID - 0231335
RN  - 0 (Immunoglobulin A)
RN  - 0 (Immunoglobulin D)
RN  - 0 (Immunoglobulin G)
RN  - 0 (Immunoglobulin M)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - Immunoglobulin A/analysis
MH  - Immunoglobulin D/analysis
MH  - *Immunoglobulin E/analysis
MH  - Immunoglobulin G/analysis
MH  - Immunoglobulin M/analysis
MH  - Male
MH  - Middle Aged
MH  - Tuberculosis, Pulmonary/*immunology
EDAT- 1976/07/11 19:15
MHDA- 2001/03/28 10:01
CRDT- 1976/07/11 19:15
PHST- 1976/07/11 19:15 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1976/07/11 19:15 [entrez]
AID - S0012-3692(16)53186-9 [pii]
AID - 10.1378/chest.70.1.21 [doi]
PST - ppublish
SO  - Chest. 1976 Jul;70(1):21-3. doi: 10.1378/chest.70.1.21.