PMID- 12787662
OWN - NLM
STAT- MEDLINE
DCOM- 20030805
LR  - 20191210
IS  - 0379-0738 (Print)
IS  - 0379-0738 (Linking)
VI  - 133
IP  - 3
DP  - 2003 May 5
TI  - Intoxication due to 1,4-butanediol.
PG  - 256-9
AB  - We report a case of intoxication resulting from the ingestion of a liquid, sold 
      in the illicit market as "liquid ecstasy," which was found to contain 
      1,4-butanediol, a metabolic precursor of gamma-hydroxybutiric acid (GHB). 
      Identification of the substance in the liquid was performed by gas 
      chromatography-mass spectrometry (GC-MS). The toxicological analysis of blood, 
      urine and gastric content of the victim was performed by immunoassay and gas 
      chromatography with nitrogen-phosphorus detection as screening techniques and by 
      means of GC-MS for confirmation and quantitation of 1,4-butanediol and GHB. The 
      following drug concentrations were found: 82 microg/ml (blood), 401 microg/ml 
      (urine) and 7.4 microg/ml (gastric content) for 1,4-butanediol and 103 microg/ml 
      (blood), 430.0 microg/ml (urine) for GHB. In addition to these, other drugs 
      detected and their blood concentration found in this case were 
      methylenedioxymethylamphetamine (MDMA) 0.23 microg/ml and its metabolite 
      methylenedioxyphenylamphetamine (MDA) 0.10 microg/ml. In the urine, a 
      concentration of 0.10 microg/ml of benzoylecgonine was also found.
FAU - Lora-Tamayo, C
AU  - Lora-Tamayo C
AD  - Instituto Nacional de Toxicologia, Ministerio de Justicia, C/ Luis Cabrera 9, 
      28002 Madrid, Spain. drogas@mad.inaltox.es
FAU - Tena, T
AU  - Tena T
FAU - Rodriguez, A
AU  - Rodriguez A
FAU - Sancho, J R
AU  - Sancho JR
FAU - Molina, E
AU  - Molina E
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Ireland
TA  - Forensic Sci Int
JT  - Forensic science international
JID - 7902034
RN  - 0 (Butylene Glycols)
RN  - 0 (Dopamine Uptake Inhibitors)
RN  - 0 (Hallucinogens)
RN  - 0 (Illicit Drugs)
RN  - 5353I8I6YS (benzoylecgonine)
RN  - 7XOO2LE6G3 (1,4-butanediol)
RN  - I5Y540LHVR (Cocaine)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Butylene Glycols/blood/*poisoning/urine
MH  - Cocaine/*analogs & derivatives/urine
MH  - Dopamine Uptake Inhibitors/urine
MH  - Gas Chromatography-Mass Spectrometry
MH  - Gastrointestinal Contents/chemistry
MH  - Hallucinogens/blood
MH  - Humans
MH  - Illicit Drugs/blood/*poisoning/urine
MH  - Male
MH  - N-Methyl-3,4-methylenedioxyamphetamine/blood
EDAT- 2003/06/06 05:00
MHDA- 2003/08/06 05:00
CRDT- 2003/06/06 05:00
PHST- 2003/06/06 05:00 [pubmed]
PHST- 2003/08/06 05:00 [medline]
PHST- 2003/06/06 05:00 [entrez]
AID - S0379073802004243 [pii]
AID - 10.1016/s0379-0738(02)00424-3 [doi]
PST - ppublish
SO  - Forensic Sci Int. 2003 May 5;133(3):256-9. doi: 10.1016/s0379-0738(02)00424-3.