PMID- 12799081
OWN - NLM
STAT- MEDLINE
DCOM- 20040525
LR  - 20191107
IS  - 1567-133X (Print)
IS  - 1567-133X (Linking)
VI  - 3
IP  - 3
DP  - 2003 Jun
TI  - Cadherin expression in the inner ear of developing zebrafish.
PG  - 337-9
AB  - Cadherins are cell adhesion molecules that have been implicated in development of 
      a variety of organs including the ear. In this study we analyzed expression 
      patterns of three zebrafish cadherins (Cadherin-2, -4, and -11) in the embryonic 
      and larval zebrafish inner ear using both in situ hybridization and 
      immunocytochemical methods. All three Cadherins exhibit distinct spatiotemporal 
      patterns of expression during otic vesicle morphogenesis. Cadherin-2 and 
      Cadherin-4 proteins and their respective mRNAs were detected mainly in the 
      sensory patches and the statoacoustic ganglion (SAg), respectively. In contrast, 
      cadherin-11mRNA was widely expressed earlier in the otic placode, and later 
      became restricted to a subset of cells in the inner ear, including hair cells.
FAU - Novince, Z M
AU  - Novince ZM
AD  - Department of Biology, University of Akron, Akron, OH 44325-3908, USA.
FAU - Azodi, E
AU  - Azodi E
FAU - Marrs, J A
AU  - Marrs JA
FAU - Raymond, P A
AU  - Raymond PA
FAU - Liu, Q
AU  - Liu Q
LA  - eng
GR  - EY04318/EY/NEI NIH HHS/United States
GR  - EY11365/EY/NEI NIH HHS/United States
GR  - EY13879/EY/NEI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Gene Expr Patterns
JT  - Gene expression patterns : GEP
JID - 101167473
RN  - 0 (Cadherins)
RN  - 0 (RNA, Messenger)
SB  - IM
MH  - Animals
MH  - Cadherins/biosynthesis/*genetics
MH  - Ear, Inner/embryology/*metabolism
MH  - Gene Expression Profiling
MH  - In Situ Hybridization
MH  - RNA, Messenger/metabolism
MH  - Zebrafish/embryology/*metabolism
EDAT- 2003/06/12 05:00
MHDA- 2004/05/27 05:00
CRDT- 2003/06/12 05:00
PHST- 2003/06/12 05:00 [pubmed]
PHST- 2004/05/27 05:00 [medline]
PHST- 2003/06/12 05:00 [entrez]
AID - S1567133X03000309 [pii]
AID - 10.1016/s1567-133x(03)00030-9 [doi]
PST - ppublish
SO  - Gene Expr Patterns. 2003 Jun;3(3):337-9. doi: 10.1016/s1567-133x(03)00030-9.