PMID- 12817826
OWN - NLM
STAT- MEDLINE
DCOM- 20031017
LR  - 20190901
IS  - 0096-882X (Print)
IS  - 0096-882X (Linking)
VI  - 64
IP  - 3
DP  - 2003 May
TI  - Alcoholic men endorse more DSM-IV withdrawal symptoms than alcoholic women 
      matched in drinking history.
PG  - 375-9
AB  - OBJECTIVE: Given gender differences in alcohol metabolism, drinking patterns and 
      alcohol-related problems, we asked whether men and women recruited for research 
      protocols from treatment programs would meet different subsets of alcohol 
      dependence or withdrawal criteria or differ in current level of functioning. 
      METHOD: The subjects were 66 men and 62 women meeting DSM-III-R or DSM-IV 
      criteria for alcohol dependence. Gender differences were tested infrequency 
      counts of criteria endorsed and Global Assessment of Functioning (GAF) scores. 
      RESULTS: All seven alcohol dependence criteria were endorsed by 50% of the 
      sample. There were no significant gender differences in frequency of individual 
      criteria endorsed. However, more men than women tended to endorse the withdrawal 
      criterion for alcohol dependence and the tremor criterion for alcohol withdrawal, 
      whereas women had higher GAF scores. When subgroups of men and women were matched 
      on alcohol consumption variables, significantly more men than women endorsed the 
      withdrawal criterion for alcohol dependence and the anxiety criterion for alcohol 
      withdrawal, and women still had significantly higher GAF scores than men. 
      CONCLUSIONS: DSM criteria provide a similar characterization of alcohol 
      dependence in male and female research volunteers. Despite this similarity, the 
      DSM criteria were sensitive to gender differences, which can now be challenged 
      with rigorous testing.
FAU - Deshmukh, Anjali
AU  - Deshmukh A
AD  - Neuroscience Program, SR International, Menlo Park, California, USA.
FAU - Rosenbloom, Margaret J
AU  - Rosenbloom MJ
FAU - Sassoon, Stephanie
AU  - Sassoon S
FAU - O'Reilly, Anne
AU  - O'Reilly A
FAU - Pfefferbaum, Adolf
AU  - Pfefferbaum A
FAU - Sullivan, Edith V
AU  - Sullivan EV
LA  - eng
GR  - AA1299/AA/NIAAA NIH HHS/United States
GR  - AA12388/AA/NIAAA NIH HHS/United States
GR  - R01 AA012388/AA/NIAAA NIH HHS/United States
GR  - AA05965/AA/NIAAA NIH HHS/United States
GR  - AA10723/AA/NIAAA NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - J Stud Alcohol
JT  - Journal of studies on alcohol
JID - 7503813
SB  - IM
MH  - Adult
MH  - Alcoholism/*diagnosis/physiopathology/psychology
MH  - Chi-Square Distribution
MH  - *Diagnostic and Statistical Manual of Mental Disorders
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Regression Analysis
MH  - *Sex Characteristics
MH  - Substance Withdrawal Syndrome/*diagnosis/physiopathology/psychology
EDAT- 2003/06/24 05:00
MHDA- 2003/10/18 05:00
CRDT- 2003/06/24 05:00
PHST- 2003/06/24 05:00 [pubmed]
PHST- 2003/10/18 05:00 [medline]
PHST- 2003/06/24 05:00 [entrez]
AID - 10.15288/jsa.2003.64.375 [doi]
PST - ppublish
SO  - J Stud Alcohol. 2003 May;64(3):375-9. doi: 10.15288/jsa.2003.64.375.