PMID- 12819848 OWN - NLM STAT- MEDLINE DCOM- 20030930 LR - 20160512 IS - 1618-2642 (Print) IS - 1618-2642 (Linking) VI - 376 IP - 4 DP - 2003 Jun TI - 15N isotopic analyses: a powerful tool to establish links between seized 3,4-methylenedioxymethamphetamine (MDMA) tablets. PG - 486-90 AB - In this study the (15)N/(14)N isotopic ratios of 43 samples of 3,4-methylenedioxymethamphetamine (MDMA) samples were measured using Gas Chromatography-Combustion-Isotope-Ratio Mass Spectrometry (GC-C-IRMS). The results show a large discrimination between samples with a range of delta(15)N values between -16 and +19 per thousand. Comparison between delta(15)N values and other physical and chemical parameters shows a strong relationship between delta(15)N and brand logo or composition. Thus, it could be assumed that tablets from different seizures probably originated from the same clandestine manufacturing source. Hence, (15)N isotopic parameters provide an important additional tool to establish common origins between seizures of clandestine synthetic drugs. FAU - Palhol, Fabien AU - Palhol F AD - Laboratoire des Douanes de Paris, 1 rue G. Vicaire, 75141, Paris Cedex 03, France. fpalhol@wanadoo.fr FAU - Lamoureux, Catherine AU - Lamoureux C FAU - Naulet, Norbert AU - Naulet N LA - eng PT - Journal Article DEP - 20030329 PL - Germany TA - Anal Bioanal Chem JT - Analytical and bioanalytical chemistry JID - 101134327 RN - 0 (Designer Drugs) RN - 0 (Nitrogen Isotopes) RN - 0 (Tablets) RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) SB - IM MH - Designer Drugs/*analysis MH - Gas Chromatography-Mass Spectrometry MH - N-Methyl-3,4-methylenedioxyamphetamine/*analysis MH - Nitrogen Isotopes MH - Reproducibility of Results MH - Tablets EDAT- 2003/06/24 05:00 MHDA- 2003/10/01 05:00 CRDT- 2003/06/24 05:00 PHST- 2002/11/04 00:00 [received] PHST- 2003/01/10 00:00 [revised] PHST- 2003/01/22 00:00 [accepted] PHST- 2003/06/24 05:00 [pubmed] PHST- 2003/10/01 05:00 [medline] PHST- 2003/06/24 05:00 [entrez] AID - 10.1007/s00216-003-1849-6 [doi] PST - ppublish SO - Anal Bioanal Chem. 2003 Jun;376(4):486-90. doi: 10.1007/s00216-003-1849-6. Epub 2003 Mar 29.