PMID- 12821028 OWN - NLM STAT- MEDLINE DCOM- 20040311 LR - 20191025 IS - 0895-6111 (Print) IS - 0895-6111 (Linking) VI - 27 IP - 5 DP - 2003 Sep-Oct TI - 3DVIEWNIX-AVS: a software package for the separate visualization of arteries and veins in CE-MRA images. PG - 351-62 AB - Our earlier study developed a computerized method, based on fuzzy connected object delineation principles and algorithms, for artery and vein separation in contrast enhanced Magnetic Resonance Angiography (CE-MRA) images. This paper reports its current development-a software package-for routine clinical use. The software package, termed 3DVIEWNIX-AVS, consists of the following major operational parts: (1) converting data from DICOM3 to 3DVIEWNIX format, (2) previewing slices and creating VOI and MIP Shell, (3) segmenting vessel, (4) separating artery and vein, (5) shell rendering vascular structures and creating animations. This package has been applied to EPIX Medical Inc's CE-MRA data (AngioMark MS-325). One hundred and thirty-five original CE-MRA data sets (of 52 patients) from 6 hospitals have been processed. In all case studies, unified parameter settings produce correct artery-vein separation. The current package is running on a Pentium PC under Linux and the total computation time per study is about 3 min. The strengths of this software package are (1) minimal user interaction, (2) minimal anatomic knowledge requirements on human vascular system, (3) clinically required speed, (4) free entry to any operational stages, (5) reproducible, reliable, high quality of results, and (6) cost effective computer implementation. To date, it seems to be the only software package (using an image processing approach) available for artery and vein separation of the human vascular system for routine use in a clinical setting. FAU - Lei, Tianhu AU - Lei T AD - Medical Image Processing Group, Department of Radiology, University of Pennsylvania, 4th floor, Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104-6021, USA. FAU - Udupa, Jayaram K AU - Udupa JK FAU - Odhner, Dewey AU - Odhner D FAU - Nyul, Laszlo G AU - Nyul LG FAU - Saha, Punam K AU - Saha PK LA - eng GR - AR 46902/AR/NIAMS NIH HHS/United States GR - NS 37172/NS/NINDS NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Comput Med Imaging Graph JT - Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society JID - 8806104 SB - IM MH - Algorithms MH - Arteries/*anatomy & histology MH - Fuzzy Logic MH - Humans MH - *Image Processing, Computer-Assisted MH - *Magnetic Resonance Angiography MH - Reproducibility of Results MH - *Software/economics MH - Veins/*anatomy & histology EDAT- 2003/06/25 05:00 MHDA- 2004/03/12 05:00 CRDT- 2003/06/25 05:00 PHST- 2003/06/25 05:00 [pubmed] PHST- 2004/03/12 05:00 [medline] PHST- 2003/06/25 05:00 [entrez] AID - S0895611103000296 [pii] AID - 10.1016/s0895-6111(03)00029-6 [doi] PST - ppublish SO - Comput Med Imaging Graph. 2003 Sep-Oct;27(5):351-62. doi: 10.1016/s0895-6111(03)00029-6.