PMID- 12826754
OWN - NLM
STAT- MEDLINE
DCOM- 20030729
LR  - 20171101
IS  - 1424-8581 (Print)
IS  - 1424-8581 (Linking)
VI  - 98
IP  - 4
DP  - 2002
TI  - Mapping the distribution of the interstitial telomeric (TTAGGG)n sequences in 
      eight species of Brazilian marsupials (Didelphidae) by FISH and the correlation 
      with constitutive heterochromatin. Do ITS represent evidence for fusion events in 
      American marsupials?
PG  - 278-84
AB  - The C-band pattern and the distribution of the (TTAGGG)(n) sequence after 
      fluorescence in situ hybridization (FISH), were studied in eight species of 
      Didelphidae marsupials: four species with 2n = 14 (Marmosops parvidens, Marmosops 
      incanus, Marmosa murina and Metachirus nudicaudatus), two species with 2n = 18 
      (Monodelphis domestica and M. americana), and two with 2n = 22 (Didelphis 
      marsupialis and Lutreolina crassicaudata). The hybridization signals were 
      observed at both termini telomeres of all chromosomes. In addition, interstitial 
      sequences were detected in the pericentromeric region of all chromosomes of 
      Marmosops parvidens, in five chromosome pairs of M. incanus, and in the first 
      pair of Monodelphis domestica. These sites always occur in the region of 
      constitutive heterochromatin, even though C-band positive regions do not always 
      present interstitial telomeric sequences (ITS). We suggest that the interstitial 
      (TTAGGG)(n) sequences are associated with satellite DNA and do not necessarily 
      arise through chromosomal rearrangements.
CI  - Copyright 2002 S. Karger AG, Basel
FAU - Pagnozzi, J M
AU  - Pagnozzi JM
AD  - Departamento de Biologia, Instituto de Biociencias, Universidade de Sao Paulo, 
      Sao Paulo, Brazil.
FAU - Ditchfield, A D
AU  - Ditchfield AD
FAU - Yonenaga-Yassuda, Y
AU  - Yonenaga-Yassuda Y
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Switzerland
TA  - Cytogenet Genome Res
JT  - Cytogenetic and genome research
JID - 101142708
RN  - 0 (DNA, Satellite)
RN  - 0 (Heterochromatin)
SB  - IM
MH  - Animals
MH  - Brazil
MH  - Chromosome Banding
MH  - DNA, Satellite/genetics
MH  - Gene Rearrangement
MH  - Heterochromatin/*genetics
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Opossums/*genetics
MH  - *Phylogeny
MH  - Telomere/*genetics
EDAT- 2003/06/27 05:00
MHDA- 2003/07/30 05:00
CRDT- 2003/06/27 05:00
PHST- 2002/12/02 00:00 [received]
PHST- 2003/03/03 00:00 [accepted]
PHST- 2003/06/27 05:00 [pubmed]
PHST- 2003/07/30 05:00 [medline]
PHST- 2003/06/27 05:00 [entrez]
AID - 71049 [pii]
AID - 10.1159/000071049 [doi]
PST - ppublish
SO  - Cytogenet Genome Res. 2002;98(4):278-84. doi: 10.1159/000071049.