PMID- 12835706 OWN - NLM STAT- MEDLINE DCOM- 20030828 LR - 20051116 IS - 1078-8956 (Print) IS - 1078-8956 (Linking) VI - 9 IP - 7 DP - 2003 Jul TI - Immunopathogenesis and immunotherapy in AIDS virus infections. PG - 861-6 AB - The heterogeneity of HIV and the different human leukocyte antigen (HLA) backgrounds of infected individuals have posed challenges to understanding the pathogenesis of HIV infection. But continuing advances in our knowledge of the role of immune responses in controlling HIV viremia should help to define goals for immune-based therapies and vaccine strategies against AIDS. FAU - Letvin, Norman L AU - Letvin NL AD - Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA. FAU - Walker, Bruce D AU - Walker BD LA - eng PT - Journal Article PT - Review PL - United States TA - Nat Med JT - Nature medicine JID - 9502015 RN - 0 (Antibodies) RN - 0 (HLA Antigens) SB - IM MH - Acquired Immunodeficiency Syndrome/*immunology/*therapy MH - Antibodies/immunology MH - HIV Infections/*immunology MH - HIV-1/*immunology/*pathogenicity MH - HLA Antigens/*immunology MH - Humans MH - Immunotherapy/*methods MH - T-Lymphocytes, Cytotoxic/immunology/virology RF - 106 EDAT- 2003/07/02 05:00 MHDA- 2003/08/29 05:00 CRDT- 2003/07/02 05:00 PHST- 2003/07/02 05:00 [pubmed] PHST- 2003/08/29 05:00 [medline] PHST- 2003/07/02 05:00 [entrez] AID - nm0703-861 [pii] AID - 10.1038/nm0703-861 [doi] PST - ppublish SO - Nat Med. 2003 Jul;9(7):861-6. doi: 10.1038/nm0703-861.