PMID- 12844451
OWN - NLM
STAT- MEDLINE
DCOM- 20030924
LR  - 20081121
IS  - 1534-5874 (Print)
IS  - 1534-5874 (Linking)
VI  - 3
IP  - 4
DP  - 2003 Aug
TI  - Genital ulcers in women.
PG  - 288-98
AB  - Women who are in a low socioeconomic status are most vulnerable to genital ulcer 
      disease (GUD). GUD is recognized as an important co-factor for acquisition of 
      HIV. GUD etiology has been elucidated in the past decade, with the availability 
      of multiplex polymerase chain reaction. Worldwide, herpes simplex virus-2 (HSV-2) 
      is the leading cause of GUD. However, mainly in women in developed countries, the 
      incidence of GUD causation by HSV-1 is rising, owing to adolescents who are HSV-1 
      naive and to increased oral sex practices. Especially in some African countries, 
      the still high prevalence of chancroid should decrease in the next decade, 
      because chancroid can easily be avoided and treated. Syphilitic ulcers seemed to 
      be almost extinct, but recently there has been a resurgence of syphilis worldwide 
      with the availability of effective HIV treatment. Development of herpes and 
      chancroid vaccines, condom use, and the provision of education and accessible 
      treatment facilities should help those women who now suffer from recurrent GUD 
      infections.
FAU - Bruisten, Sylvia M
AU  - Bruisten SM
AD  - GG&GD Municipal Health Service, Department of Public Health Laboratory, Nieuwe 
      Achtergracht 100, 1018 WT Amsterdam, The Netherlands. sbruisten@gggd.amsterdam.nl
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Womens Health Rep
JT  - Current women's health reports
JID - 101120027
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Chancroid/epidemiology
MH  - Comorbidity
MH  - Disease Transmission, Infectious/prevention & control
MH  - Female
MH  - Genital Diseases, Female/diagnosis/*epidemiology/prevention & control
MH  - HIV Infections/epidemiology
MH  - Herpes Simplex/epidemiology
MH  - Humans
MH  - Incidence
MH  - Prevalence
MH  - Risk Factors
MH  - Sexually Transmitted Diseases/diagnosis/*epidemiology/prevention & 
      control/transmission
MH  - Syphilis/epidemiology
MH  - Ulcer/diagnosis/*epidemiology/prevention & control
MH  - *Women's Health
RF  - 61
EDAT- 2003/07/08 05:00
MHDA- 2003/09/25 05:00
CRDT- 2003/07/08 05:00
PHST- 2003/07/08 05:00 [pubmed]
PHST- 2003/09/25 05:00 [medline]
PHST- 2003/07/08 05:00 [entrez]
PST - ppublish
SO  - Curr Womens Health Rep. 2003 Aug;3(4):288-98.