PMID- 12854055 OWN - NLM STAT- MEDLINE DCOM- 20030903 LR - 20190901 IS - 0271-3683 (Print) IS - 0271-3683 (Linking) VI - 26 IP - 5 DP - 2003 May TI - Long term follow-up of retinal nerve fiber layer thickness in eyes with optic nerve head drusen. PG - 277-80 AB - PURPOSE: To investigate the effect of optic nerve head drusen (ONHD) on the retinal nerve fiber layer (RNFL) thickness during follow-up period. METHODS: Twenty-three non-glaucomatous eyes having clinically visible ONHD confirmed by colored disc photos were studied. RNFL thickness was determined with Optical Coherence Tomography (OCT). Eyes were re-examined after average of 18 months (ranging between 14 and 22 months). Mean RNFL thickness of each quadrant was compared with previous results at each follow-up visit. RESULTS: Mean RNFL thickness was 88.43 +/- 10.2 micron at first visit and 90.35 +/- 6.9 micron at follow-up in eyes with clinically visible ONHD. The difference between the mean RNFL thickness measured from inferior, superior, nasal and temporal quadrant at first and follow-up visits was not significant (paired t-test, p > 0.05). CONCLUSION: The presence of drusen was found to have no effect on RNFL thickness at follow-up visits. OCT may provide a useful means to evaluate and follow up the RNFL thickness in these patients. FAU - Ocakoglu, Ozcan AU - Ocakoglu O AD - Medical School of Cerrahpasa, Department of Ophthalmology, Istanbul University, Istanbul, Turkey. ocakoglu@superonline.com FAU - Ustundag, Can AU - Ustundag C FAU - Koyluoglu, Nilufer AU - Koyluoglu N FAU - Oguz, Velittin AU - Oguz V FAU - Kendiroglu, Gurhan AU - Kendiroglu G FAU - Ozkan, Sehirbay AU - Ozkan S LA - eng PT - Journal Article PL - England TA - Curr Eye Res JT - Current eye research JID - 8104312 SB - IM MH - Adult MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Nerve Fibers/*pathology MH - Optic Disk Drusen/*pathology/physiopathology MH - Optics and Photonics MH - Retina/*pathology MH - Time Factors MH - Tomography MH - Visual Acuity MH - Visual Fields EDAT- 2003/07/11 05:00 MHDA- 2003/09/04 05:00 CRDT- 2003/07/11 05:00 PHST- 2003/07/11 05:00 [pubmed] PHST- 2003/09/04 05:00 [medline] PHST- 2003/07/11 05:00 [entrez] AID - 10.1076/ceyr.26.4.277.15428 [doi] PST - ppublish SO - Curr Eye Res. 2003 May;26(5):277-80. doi: 10.1076/ceyr.26.4.277.15428.