PMID- 12868968
OWN - NLM
STAT- MEDLINE
DCOM- 20040206
LR  - 20190721
IS  - 0105-1873 (Print)
IS  - 0105-1873 (Linking)
VI  - 48
IP  - 5
DP  - 2003 May
TI  - Comparative evaluation of Type 1 latex hypersensitivity in patients with chronic 
      urticaria, rubber factory workers and healthy control subjects.
PG  - 266-71
AB  - Latex hypersensitivity manifests itself most commonly with contact urticaria. In 
      this study, we investigated the frequency of latex hypersensitivity as a possible 
      aetiological factor in patients with chronic urticaria (CU) and compared latex 
      hypersensitivity of CU patients (n = 50) with that of rubber factory workers (n = 
      50) and healthy controls (n = 50). Prick test with latex and fruit extracts and 
      determination of latex-specific immunoglobulin E (IgE) were performed. As a risk 
      factor, contact dermatitis due to rubber additives was tested by patch test. 
      Latex hypersensitivity was detected in 14% of CU patients, 12% of rubber factory 
      workers and 12% of healthy controls (P > 0.05). Positive patch test with rubber 
      additives was detected in 6% of CU and 4% of rubber factory workers. 3 of 7 CU 
      patients had sensitivity to fruits in addition to latex hypersensitivity. In 1 
      patient with CU, the clinical complaints were found to be related to latex 
      hypersensitivity. These findings suggest that the frequency of latex 
      hypersensitivity in CU patients is no higher than that in healthy individuals. 
      However, CU patients should be carefully asked about latex allergy, as we 
      demonstrated that 1 of the CU patients had undiagnosed symptomatic latex allergy.
FAU - Piskin, Gamze
AU  - Piskin G
AD  - Department of Dermatology, Faculty of Medicine, Ankara University, Ankara, 
      Turkey. g.piskin@amc.uva.nl
FAU - Akyol, Aynur
AU  - Akyol A
FAU - Uzar, Hatice
AU  - Uzar H
FAU - Tulek, Necla
AU  - Tulek N
FAU - Boyvat, Ayse
AU  - Boyvat A
FAU - Gurgey, Erbak
AU  - Gurgey E
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - Contact Dermatitis
JT  - Contact dermatitis
JID - 7604950
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Case-Control Studies
MH  - Chronic Disease
MH  - Dermatitis, Occupational/*epidemiology/etiology
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/blood
MH  - Intradermal Tests
MH  - Latex Hypersensitivity/chemically induced/*epidemiology
MH  - Male
MH  - Middle Aged
MH  - Patch Tests
MH  - Prevalence
MH  - Turkey/epidemiology
MH  - *Urticaria
EDAT- 2003/07/19 05:00
MHDA- 2004/02/10 05:00
CRDT- 2003/07/19 05:00
PHST- 2003/07/19 05:00 [pubmed]
PHST- 2004/02/10 05:00 [medline]
PHST- 2003/07/19 05:00 [entrez]
AID - 112 [pii]
AID - 10.1034/j.1600-0536.2003.00112.x [doi]
PST - ppublish
SO  - Contact Dermatitis. 2003 May;48(5):266-71. doi: 10.1034/j.1600-0536.2003.00112.x.