PMID- 12877232 OWN - NLM STAT- MEDLINE DCOM- 20031120 LR - 20151119 IS - 1085-5629 (Print) IS - 1085-5629 (Linking) VI - 22 IP - 2 DP - 2003 Jun TI - Botulinum neurotoxin type B--a rapid wrinkle reducer. PG - 131-5 AB - Botulinum toxin has been used for temporary muscle paralysis for over 13 years. The off label use of neurotoxins include treatment of dynamic lines on the face and treatment of hyperhidrosis. Several forms of botulinum toxin exist, but only 2 serotypes are available commercially. Botulinum toxin B (BoTX B) is a recently US Food and Drug Administration (FDA) approved neurotoxin used for the treatment of cervical dystonia. Investigations into the use of BoTX B for skin rejuvenation have shown rapid paralysis and reduction of wrinkles. This overview highlights the current reports on the efficacy, duration, and safety of BoTX B when used for cosmetic procedures. FAU - Jacob, Carolyn I AU - Jacob CI AD - Advanced Skin and Mohs Surgery Center, Skokie, IL 60076, USA. carriejacob@ix.netcom.com LA - eng PT - Journal Article PT - Review PL - United States TA - Semin Cutan Med Surg JT - Seminars in cutaneous medicine and surgery JID - 9617260 RN - 0 (Neuromuscular Agents) RN - 0Y70779M1F (rimabotulinumtoxinB) RN - EC 3.4.24.69 (Botulinum Toxins) RN - EC 3.4.24.69 (Botulinum Toxins, Type A) SB - IM MH - Botulinum Toxins/*administration & dosage MH - Botulinum Toxins, Type A MH - *Cosmetic Techniques MH - Dose-Response Relationship, Drug MH - Humans MH - Neuromuscular Agents/*administration & dosage MH - Rhytidoplasty/*methods MH - Skin Aging/*drug effects RF - 17 EDAT- 2003/07/25 05:00 MHDA- 2003/12/03 05:00 CRDT- 2003/07/25 05:00 PHST- 2003/07/25 05:00 [pubmed] PHST- 2003/12/03 05:00 [medline] PHST- 2003/07/25 05:00 [entrez] AID - S1085-5629(03)80016-0 [pii] AID - 10.1053/sder.2003.50009 [doi] PST - ppublish SO - Semin Cutan Med Surg. 2003 Jun;22(2):131-5. doi: 10.1053/sder.2003.50009.