PMID- 12892458 OWN - NLM STAT- MEDLINE DCOM- 20030822 LR - 20191210 IS - 1344-4964 (Print) IS - 1344-4964 (Linking) VI - 51 IP - 7 DP - 2003 Jul TI - Late results of mitral valve repair for mitral regurgitation. PG - 282-8 AB - OBJECTIVE: This study was undertaken to evaluate the long-term results of mitral valve repair for mitral regurgitation. METHODS: Between 1991 and 2000, 301 patients with mitral regurgitation underwent mitral valve repair. There were 167 men and 134 women whose mean age was 56 +/- 14 years. The patients were comprised of 7 patients in Carpentier's type I, 277 patients in type II, and 17 patients in type III. Chordal replacement with expanded polytetrafluoroethylene sutures had been prospectively applied to repair the anterior mitral leaflet prolapse. Ring annuloplasty was performed in 230 patients (76%). The follow-up was complete and mean follow-up was 67 +/- 33 months, for a cumulative follow-up of 1,624 patient-years. RESULTS: There were 5 hospital deaths and 11 late deaths (2 cardiac and 9 noncardiac). All survivors except those with stroke were in the New York Heart Association (NYHA) functional class I or II. At 10 years, the actuarial survival was 90 +/- 3%, the freedom from embolism was 86 +/- 4%, the freedom from reoperation was 96 +/- 2%, and the freedom from valve-related events was 77 +/- 4%. At 10 years, the freedom from reoperation in the patients with anterior leaflet prolapse was 90 +/- 5%. CONCLUSIONS: Mitral valve repair is feasible in most patients with mitral regurgitation and is associated with low mortality and low rates of valve related events. Chordal replacement with expanded polytetrafluoroethylene sutures is effective, safe, and durable at long-term follow-up for patients with anterior leaflet prolapse. FAU - Okada, Yukikatsu AU - Okada Y AD - Department of Thoracic and Cardiovascular Surgery, Kobe General Hospital, Kobe, Japan. FAU - Nasu, Michihiro AU - Nasu M FAU - Takahashi, Yutaka AU - Takahashi Y FAU - Handa, Nobuhiro AU - Handa N FAU - Fujiwara, Hiroshi AU - Fujiwara H FAU - Shinkai, Masahiko AU - Shinkai M FAU - Shomura, Yu AU - Shomura Y FAU - Wakiyama, Hidetaka AU - Wakiyama H FAU - Tsuda, Shouichi AU - Tsuda S LA - eng PT - Comparative Study PT - Evaluation Study PT - Journal Article PL - Japan TA - Jpn J Thorac Cardiovasc Surg JT - The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi JID - 100884261 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - *Cardiopulmonary Bypass MH - Female MH - Follow-Up Studies MH - Hospital Mortality MH - Humans MH - Japan MH - Male MH - Middle Aged MH - Mitral Valve/*surgery MH - Mitral Valve Insufficiency/mortality/*surgery MH - Postoperative Complications/etiology/mortality MH - Reoperation MH - Time Factors MH - Treatment Outcome EDAT- 2003/08/02 05:00 MHDA- 2003/08/23 05:00 CRDT- 2003/08/02 05:00 PHST- 2003/08/02 05:00 [pubmed] PHST- 2003/08/23 05:00 [medline] PHST- 2003/08/02 05:00 [entrez] AID - 10.1007/BF02719379 [doi] PST - ppublish SO - Jpn J Thorac Cardiovasc Surg. 2003 Jul;51(7):282-8. doi: 10.1007/BF02719379.