PMID- 12905095 OWN - NLM STAT- MEDLINE DCOM- 20050404 LR - 20131121 IS - 0172-4622 (Print) IS - 0172-4622 (Linking) VI - 24 IP - 6 DP - 2003 Aug TI - Effect of carbohydrate feeding during recovery from prolonged running on muscle glycogen metabolism during subsequent exercise. PG - 452-8 AB - This study examined the effect of carbohydrate (CHO) intake during a 4 h recovery from prolonged running on muscle glycogen metabolism during subsequent exercise. On 2 occasions, 7 male subjects ran for 90 min at 70 % maximum oxygen uptake VO(2 max) on a motorized treadmill (R1) followed by a 4 h rest period (REC) and a 15 min run (R2) consisting of 5 min at 60 % and 10 min at 70 % VO(2 max) During REC, each subject ingested a total of 2.7 l of an isotonic solution containing either 50 g of CHO (LOW) or 175 g of CHO (HIGH). Biopsy samples were obtained from the vastus lateralis immediately after R1, REC and R2. During REC, a higher muscle glycogen resynthesis was observed in HIGH when compared with LOW trial (75 +/- 20 vs. 31 +/- 11 mmol x kg dry matter (dm) -1, respectively; p < 0.01). Muscle glycogen utilization during R2 was similar between the HIGH and LOW trials (39 +/- 10 vs. 46 +/- 11 mmol x kg dm -1, respectively). These results suggest that ingestion of a large amount of CHO at frequent intervals during recovery from exercise does not affect the rate of muscle glycogen utilization during subsequent exercise. FAU - Tsintzas, K AU - Tsintzas K AD - Human Muscle Metabolism Research Group, Loughborough University, Loughborough, UK. FAU - Williams, C AU - Williams C FAU - Boobis, L AU - Boobis L FAU - Symington, S AU - Symington S FAU - Moorehouse, J AU - Moorehouse J FAU - Garcia-Roves, P AU - Garcia-Roves P FAU - Nicholas, C AU - Nicholas C LA - eng PT - Clinical Trial PT - Journal Article PT - Randomized Controlled Trial PL - Germany TA - Int J Sports Med JT - International journal of sports medicine JID - 8008349 RN - 0 (Blood Glucose) RN - 0 (Dietary Carbohydrates) RN - 0 (Fatty Acids, Nonesterified) RN - 0 (Insulin) RN - 33X04XA5AT (Lactic Acid) RN - 9005-79-2 (Glycogen) RN - S88TT14065 (Oxygen) SB - IM MH - Adult MH - Blood Glucose/metabolism MH - Cross-Over Studies MH - Dietary Carbohydrates/*pharmacology MH - Double-Blind Method MH - Fatty Acids, Nonesterified/blood MH - Glycogen/*metabolism MH - Heart Rate MH - Humans MH - Insulin/blood MH - Lactic Acid/metabolism MH - Male MH - Muscle, Skeletal/blood supply/*metabolism MH - Oxygen/metabolism MH - Plasma Volume MH - *Running EDAT- 2003/08/09 05:00 MHDA- 2005/04/05 09:00 CRDT- 2003/08/09 05:00 PHST- 2003/08/09 05:00 [pubmed] PHST- 2005/04/05 09:00 [medline] PHST- 2003/08/09 05:00 [entrez] AID - 10.1055/s-2003-41181 [doi] PST - ppublish SO - Int J Sports Med. 2003 Aug;24(6):452-8. doi: 10.1055/s-2003-41181.