PMID- 12918983
OWN - NLM
STAT- MEDLINE
DCOM- 20031021
LR  - 20190717
IS  - 0003-2700 (Print)
IS  - 0003-2700 (Linking)
VI  - 75
IP  - 10
DP  - 2003 May 15
TI  - Simultaneous determination of the size and surface charge of individual 
      nanoparticles using a carbon nanotube-based Coulter counter.
PG  - 2399-406
AB  - A resistive-pulse Coulter counter based on a membrane containing a single 
      multiwall carbon nanotube (MWNT) channel was used to simultaneously determine the 
      size and surface charge of carboxy-terminated polystyrene nanoparticles. The 
      membrane was prepared from an epoxy section containing a MWNT channel mounted on 
      a poly(dimethylsiloxane) (PDMS) support structure. The PDMS support reduced the 
      background noise level by a factor of > 20 compared to the Si/Si3N4 support 
      structure used in our previous study. The lower noise level makes it possible to 
      accurately measure the height and width of resistive-pulse signals resulting from 
      transport of individual particles through the MWNT channel. Particle sizes, 
      calculated from current pulse heights, were comparable to those determined by 
      transmission electron microscope (TEM). The width of the current pulses is a 
      measure of the nanoparticle transport time, and it permits calculation of the 
      electrokinetic surface charge. Different types of polystyrene nanoparticles 
      having nearly the same size, but different electrokinetic surface charge, could 
      be resolved on the basis of the difference in their transport time.
FAU - Ito, Takashi
AU  - Ito T
AD  - Department of Chemistry, Texas A&M University, P.O. Box 30012, College Station, 
      Texas 77842-3012, USA.
FAU - Sun, Li
AU  - Sun L
FAU - Crooks, Richard M
AU  - Crooks RM
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - United States
TA  - Anal Chem
JT  - Analytical chemistry
JID - 0370536
RN  - 0 (Nanotubes, Carbon)
RN  - 0 (Polystyrenes)
SB  - IM
MH  - Electric Impedance
MH  - Equipment Design
MH  - Nanotubes, Carbon/*chemistry
MH  - Particle Size
MH  - Polystyrenes/*analysis/chemistry
MH  - Sensitivity and Specificity
EDAT- 2003/08/16 05:00
MHDA- 2003/10/22 05:00
CRDT- 2003/08/16 05:00
PHST- 2003/08/16 05:00 [pubmed]
PHST- 2003/10/22 05:00 [medline]
PHST- 2003/08/16 05:00 [entrez]
AID - 10.1021/ac034072v [doi]
PST - ppublish
SO  - Anal Chem. 2003 May 15;75(10):2399-406. doi: 10.1021/ac034072v.