PMID- 12919125
OWN - NLM
STAT- MEDLINE
DCOM- 20031021
LR  - 20191107
IS  - 1396-0296 (Print)
IS  - 1396-0296 (Linking)
VI  - 16
IP  - 1
DP  - 2003
TI  - Diagnosis and treatment of actinic prurigo.
PG  - 40-4
AB  - Actinic prurigo (AP) is an idiopathic photodermatosis that affects mainly the 
      mestizo population in Latin America. It has an early onset, a slight predominance 
      in women, and affects the sun-exposed areas of the skin, causing erythematous 
      papules and lichenified plaques secondary to intense and chronic pruritus. 
      Lesions can be induced by both ultraviolet A (UVA) and ultraviolet B (UVB). An 
      association with several human leukocyte antigen (HLA) alleles has been reported. 
      AP is unique among all photodermatoses in its remarkable response to thalidomide. 
      In the past the microscopic features of AP have been considered as nonspecific; 
      however, the constant finding of dense lymphocytic inflammatory infiltrates and 
      the immunogenetic features of AP support the existence of an immunologic 
      mechanism in its pathogenesis.
FAU - Hojyo-Tomoka, Maria-Teresa
AU  - Hojyo-Tomoka MT
AD  - Department of Dermatology, Hospital General "Dr. Manuel Gea Gonzalez," Mexico 
      City, Mexico. dermagea@prodigy.net.mx
FAU - Vega-Memije, Maria-Elisa
AU  - Vega-Memije ME
FAU - Cortes-Franco, Roberto
AU  - Cortes-Franco R
FAU - Dominguez-Soto, Luciano
AU  - Dominguez-Soto L
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Dermatol Ther
JT  - Dermatologic therapy
JID - 9700070
RN  - 0 (Dermatologic Agents)
RN  - 4Z8R6ORS6L (Thalidomide)
SB  - IM
MH  - Dermatologic Agents/therapeutic use
MH  - Diagnosis, Differential
MH  - Humans
MH  - Photosensitivity Disorders/*diagnosis/drug therapy/immunology
MH  - Prurigo/*diagnosis/drug therapy/immunology
MH  - Thalidomide/therapeutic use
RF  - 16
EDAT- 2003/08/16 05:00
MHDA- 2003/10/22 05:00
CRDT- 2003/08/16 05:00
PHST- 2003/08/16 05:00 [pubmed]
PHST- 2003/10/22 05:00 [medline]
PHST- 2003/08/16 05:00 [entrez]
AID - 01606 [pii]
AID - 10.1046/j.1529-8019.2003.01606.x [doi]
PST - ppublish
SO  - Dermatol Ther. 2003;16(1):40-4. doi: 10.1046/j.1529-8019.2003.01606.x.