PMID- 12930250
OWN - NLM
STAT- MEDLINE
DCOM- 20040105
LR  - 20191210
IS  - 1045-3873 (Print)
IS  - 1045-3873 (Linking)
VI  - 14
IP  - 7
DP  - 2003 Jul
TI  - Atrial noninvasive activation mapping of paced rhythm data.
PG  - 712-9
AB  - INTRODUCTION: Atrial arrhythmias have emerged as a topic of great interest for 
      clinical electrophysiologists. Noninvasive imaging of electrical function in 
      humans may be useful for computer-aided diagnosis and treatment of cardiac 
      arrhythmias, which can be accomplished by the fusion of data from ECG mapping and 
      magnetic resonance imaging (MRI). METHODS AND RESULTS: In this study, a 
      bidomain-theory-based surface heart model activation time (AT) imaging approach 
      was applied to paced rhythm data from four patients. Pacing sites were the right 
      superior pulmonary vein, left inferior pulmonary vein, left superior pulmonary 
      vein, coronary sinus, posterior wall of right atrium, and high right atrium. For 
      coronary sinus pacing, the AT pattern of the right atrium was compared with a 
      CARTO map. The root mean square error between CARTO geometry (85 nodal points) 
      and the surface model of the right atrium was 8.6 mm. The correlation coefficient 
      of the noninvasively obtained AT map of the right atrium and the CARTO map was 
      0.76. All pulmonary vein pacing sites were identified. The reconstructed pacing 
      site of right posterior atrial pacing correlates with the invasively determined 
      pacing catheter position with a localization distance of 4 mm. CONCLUSION: The 
      individual anatomic model of the atria of each patient enables accurate 
      noninvasive AT imaging within the atria, resulting in a localization error for 
      the pacing sites within 10 mm. Our findings may have implications for imaging of 
      atrial activity in patients with focal arrhythmias or focal triggers.
FAU - Modre, Robert
AU  - Modre R
AD  - Institute for Medical Signal Processing and Imaging, University for Health 
      Informatics and Technology Tyrol, Innrain 98, 6020 Innsbruck, Austria. 
      robert.modre@umit.at
FAU - Tilg, Bernhard
AU  - Tilg B
FAU - Fischer, Gerald
AU  - Fischer G
FAU - Hanser, Friedrich
AU  - Hanser F
FAU - Messnarz, Bernd
AU  - Messnarz B
FAU - Seger, Michael
AU  - Seger M
FAU - Schocke, Michael F H
AU  - Schocke MF
FAU - Berger, Thomas
AU  - Berger T
FAU - Hintringer, Florian
AU  - Hintringer F
FAU - Roithinger, Franz X
AU  - Roithinger FX
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
PT  - Validation Study
PL  - United States
TA  - J Cardiovasc Electrophysiol
JT  - Journal of cardiovascular electrophysiology
JID - 9010756
SB  - IM
CIN - J Cardiovasc Electrophysiol. 2003 Jul;14(7):720-1. PMID: 12930251
MH  - Adult
MH  - Atrial Fibrillation/*physiopathology
MH  - Body Surface Potential Mapping/*methods
MH  - *Cardiac Pacing, Artificial
MH  - Computer Simulation
MH  - Diagnosis, Computer-Assisted/*methods
MH  - Female
MH  - Heart Atria/*physiopathology
MH  - Heart Conduction System/*physiopathology
MH  - Humans
MH  - Magnetic Resonance Imaging/methods
MH  - Male
MH  - Middle Aged
MH  - *Models, Cardiovascular
MH  - Models, Neurological
EDAT- 2003/08/22 05:00
MHDA- 2004/01/06 05:00
CRDT- 2003/08/22 05:00
PHST- 2003/08/22 05:00 [pubmed]
PHST- 2004/01/06 05:00 [medline]
PHST- 2003/08/22 05:00 [entrez]
AID - 02558 [pii]
AID - 10.1046/j.1540-8167.2003.02558.x [doi]
PST - ppublish
SO  - J Cardiovasc Electrophysiol. 2003 Jul;14(7):712-9. doi: 
      10.1046/j.1540-8167.2003.02558.x.