PMID- 12931293 OWN - NLM STAT- MEDLINE DCOM- 20040519 LR - 20191210 IS - 1090-3941 (Print) IS - 1090-3941 (Linking) VI - 11 DP - 2003 TI - The Stretta procedure: effective endoluminal therapy for GERD. PG - 129-34 AB - Since its inception, laparoscopic fundoplication has revolutionized the surgical approach to gastroesophageal reflux disease (GERD). Endoluminal therapies for GERD are less invasive than surgery, seek to duplicate its efficacy, and may eliminate reliance on proton pump inhibitors (PPI) and other antisecretory drugs. The Stretta procedure uses radiofrequency (RF) energy delivered to the tissues of the distal lower esophageal sphincter (LES) and gastric cardia, which decreases LES compliance, increases LES muscle mass, and limits the inappropriate transient LES relaxations responsible for GERD in many patients. The Stretta procedure has been shown to be effective in laboratory studies, randomized sham-controlled studies, and numerous open-label prospective clinical trials. For patients with appropriate indications, the Stretta procedure is an effective endoluminal therapy for treatment of symptomatic GERD. FAU - Fanelli, Robert D AU - Fanelli RD AD - Department of Surgery, Berkshire Medical Center, University of Massachusetts Medical School, Pittsfield, MA, USA. FAU - Gersin, Keith S AU - Gersin KS FAU - Bakhsh, Adel AU - Bakhsh A LA - eng PT - Comparative Study PT - Journal Article PT - Review PL - United States TA - Surg Technol Int JT - Surgical technology international JID - 9604509 SB - IM MH - Esophagogastric Junction/radiation effects MH - *Esophagoscopes MH - Esophagoscopy/*methods MH - Female MH - Follow-Up Studies MH - Fundoplication/methods MH - Gastroesophageal Reflux/diagnosis/*surgery MH - Humans MH - Male MH - Minimally Invasive Surgical Procedures/methods MH - *Quality of Life MH - Radiofrequency Therapy MH - Randomized Controlled Trials as Topic MH - Risk Assessment MH - Sensitivity and Specificity MH - Severity of Illness Index MH - Treatment Outcome RF - 17 EDAT- 2003/08/22 05:00 MHDA- 2004/05/20 05:00 CRDT- 2003/08/22 05:00 PHST- 2003/08/22 05:00 [pubmed] PHST- 2004/05/20 05:00 [medline] PHST- 2003/08/22 05:00 [entrez] PST - ppublish SO - Surg Technol Int. 2003;11:129-34.