PMID- 12934169 OWN - NLM STAT- MEDLINE DCOM- 20030930 LR - 20071115 IS - 0012-0472 (Print) IS - 0012-0472 (Linking) VI - 128 IP - 34-35 DP - 2003 Aug 22 TI - [The Ross procedure (pulmonary autograft) as an alternative for aortic valve replacement]. PG - 1759-64 AB - BACKGROUND AND OBJECTIVE: The Ross procedure (pulmonary autograft) has since the 1980s attracted growing interest as an alternative to the widely practised insertion of a prosthetic aortic valve. The 12-year experience of a consecutive series from one centre are reported here. PATIENTS AND METHODS: Between February 1990 and January 2002 a Ross procedure, predominantly with the subcoronary technique, was performed in 244 consecutive patients with aortic valve disease (244 men, 54 women, mean age 46 +/- 13.5 years). Annual follow-up clinical examinations (mean postoperative period 32.9 +/- 29.5 months in 99 % of the cohort) were performed. RESULTS: Perioperative mortality was 0.8 % (n=2), and there were two late deaths unrelated to the aortic valve disease. Seven patients had to be re-operated for failure of the homograft (n=4) or autograft (n=4). According to clinical criteria, 99 % of the followed-up patients were in New York Heart Association (NYHA) functional class I or II, only two patients, with pulmonary comorbidity, were in class III. Echocardiography demonstrated autografts with nearly normal transvalvular gradient (mean maximal pressure gradient 6.5 +/- 3.3 mmHg), while nine patients had second-degree aortic regurgitation. The mean maximal gradient across the homograft valve in the pulmonary position was 12.0 +/- 6.9 mmHg, while ten patients had second-degree and one had third-degree pulmonary regurgitation. CONCLUSION: The technically demanding Ross procedure produced excellent clinical and hemodynamic mid-term results. It is thus an appealing alternative to the widely used replacement by a prosthetic valve. Definitive assessment awaits further long-term follow-up. FAU - Schmidtke, C AU - Schmidtke C AD - Klinik fur Herzchirurgie, Universitatsklinikum Schleswig-Holstein, Campus Lubeck. schmidtk@medinf.mu-luebeck.de FAU - Stierle, U AU - Stierle U FAU - Sievers, H-H AU - Sievers HH FAU - Graf, B AU - Graf B LA - ger PT - Comparative Study PT - English Abstract PT - Journal Article TT - Die Ross-Operation (pulmonaler Autograft) als alternativer Aortenklappenersatz. PL - Germany TA - Dtsch Med Wochenschr JT - Deutsche medizinische Wochenschrift (1946) JID - 0006723 SB - IM MH - Adult MH - Aged MH - Aortic Valve Insufficiency/physiopathology/*surgery MH - Aortic Valve Stenosis/physiopathology/*surgery MH - Cohort Studies MH - Data Interpretation, Statistical MH - Echocardiography, Doppler MH - Female MH - Follow-Up Studies MH - Hemodynamics MH - Humans MH - Male MH - Middle Aged MH - Pulmonary Valve/*transplantation MH - Reoperation MH - Time Factors MH - Transplantation, Autologous EDAT- 2003/08/23 05:00 MHDA- 2003/10/01 05:00 CRDT- 2003/08/23 05:00 PHST- 2003/08/23 05:00 [pubmed] PHST- 2003/10/01 05:00 [medline] PHST- 2003/08/23 05:00 [entrez] AID - 10.1055/s-2003-41707 [doi] PST - ppublish SO - Dtsch Med Wochenschr. 2003 Aug 22;128(34-35):1759-64. doi: 10.1055/s-2003-41707.