PMID- 12948732
OWN - NLM
STAT- MEDLINE
DCOM- 20031023
LR  - 20191107
IS  - 1053-8119 (Print)
IS  - 1053-8119 (Linking)
VI  - 19
IP  - 4
DP  - 2003 Aug
TI  - Comparison of BOLD fMRI and MEG characteristics to vibrotactile stimulation.
PG  - 1778-86
AB  - The characteristics of blood oxygenation level-dependent (BOLD) fMRI and 
      magnetoencephalographic (MEG) responses to vibrotactile stimuli in humans were 
      studied and compared. The stimuli, presented with interstimulus intervals (ISIs) 
      ranging from 1 to 5 s, yielded highly reproducible MEG responses, with current 
      dipoles in the primary somatosensory (SI) cortex in all subjects. BOLD fMRI 
      responses to similar stimuli showed substantial intrasubject variation in the 
      activation sites around the SI cortex. BOLD responses were detected in all 
      subjects in the secondary somatosensory (SII) cortices as well, with comparable 
      BOLD response amplitudes to those in the SI cortex. Current dipoles, used to 
      model the MEG signals, were stronger at longer ISIs than shorter ISIs. The BOLD 
      response amplitudes did not show a similar dependence on ISI, but the activated 
      brain area was larger when longer ISIs or longer stimuli were applied. Our 
      results support the view that combined use of brain mapping methods provides 
      complementary information and should be considered in functional brain 
      examinations.
FAU - Tuunanen, Pasi I
AU  - Tuunanen PI
AD  - Department of Biomedical NMR and National Bio-NMR Facility, University of Kuopio, 
      Finland.
FAU - Kavec, Martin
AU  - Kavec M
FAU - Jousmaki, Veikko
AU  - Jousmaki V
FAU - Usenius, Jussi-Pekka
AU  - Usenius JP
FAU - Hari, Riitta
AU  - Hari R
FAU - Salmelin, Riitta
AU  - Salmelin R
FAU - Kauppinen, Risto A
AU  - Kauppinen RA
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Neuroimage
JT  - NeuroImage
JID - 9215515
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Adult
MH  - Arousal/physiology
MH  - Brain Mapping
MH  - Female
MH  - Humans
MH  - Image Enhancement/*methods
MH  - Image Processing, Computer-Assisted/*methods
MH  - Magnetic Resonance Imaging/*methods
MH  - Magnetoencephalography/*methods
MH  - Male
MH  - Middle Aged
MH  - Oxygen/*blood
MH  - Reaction Time/physiology
MH  - *Signal Processing, Computer-Assisted
MH  - Somatosensory Cortex/anatomy & histology/*physiology
MH  - Touch/*physiology
MH  - Vibration
EDAT- 2003/09/02 05:00
MHDA- 2003/10/24 05:00
CRDT- 2003/09/02 05:00
PHST- 2003/09/02 05:00 [pubmed]
PHST- 2003/10/24 05:00 [medline]
PHST- 2003/09/02 05:00 [entrez]
AID - S1053811903002568 [pii]
AID - 10.1016/s1053-8119(03)00256-8 [doi]
PST - ppublish
SO  - Neuroimage. 2003 Aug;19(4):1778-86. doi: 10.1016/s1053-8119(03)00256-8.