PMID- 12952238 OWN - NLM STAT- MEDLINE DCOM- 20040316 LR - 20190116 IS - 1042-8194 (Print) IS - 1026-8022 (Linking) VI - 44 IP - 8 DP - 2003 Aug TI - Immune reconstitution inflammatory syndrome mimicking relapse of AIDS related lymphoma in patients with HIV 1 infection. PG - 1417-9 AB - People with HIV infection who commence highly active antiretroviral therapy (HAART) occasionally develop reactivation of subclinical infection. This clinical entity is termed immune reconstitution inflammatory syndrome (IRIS) and is defined as a paradoxical deterioration in clinical status as a result of recovery of the immune system during HAART. We present three cases of IRIS following a diagnosis of AIDS related non-Hodgkin's lymphoma that resembled lymphoma relapse. FAU - Powles, T AU - Powles T AD - Departments of Oncology and HIV medicine, Chelsea and Westminster Hospital, 369 Fulham Road, London SW10 9NH, UK. FAU - Thirlwell, C AU - Thirlwell C FAU - Nelson, M AU - Nelson M FAU - Bower, M AU - Bower M LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Leuk Lymphoma JT - Leukemia & lymphoma JID - 9007422 SB - IM MH - Adult MH - Antiretroviral Therapy, Highly Active/adverse effects MH - Bacterial Infections/chemically induced/*diagnosis/pathology MH - Diagnosis, Differential MH - HIV Infections/*complications/drug therapy MH - Humans MH - Immune System/*microbiology/pathology/physiology MH - Inflammation/*diagnosis/microbiology MH - Lymphoma, AIDS-Related/*diagnosis MH - Male MH - Mycobacterium avium-intracellulare Infection/chemically induced/diagnosis/pathology MH - Neck/microbiology/pathology MH - Recurrence MH - Regeneration MH - Syndrome EDAT- 2003/09/04 05:00 MHDA- 2004/03/17 05:00 CRDT- 2003/09/04 05:00 PHST- 2003/09/04 05:00 [pubmed] PHST- 2004/03/17 05:00 [medline] PHST- 2003/09/04 05:00 [entrez] AID - 10.1080/1042819031000083280 [doi] PST - ppublish SO - Leuk Lymphoma. 2003 Aug;44(8):1417-9. doi: 10.1080/1042819031000083280.