PMID- 12962413
OWN - NLM
STAT- MEDLINE
DCOM- 20031009
LR  - 20230315
IS  - 1344-4964 (Print)
IS  - 1344-4964 (Linking)
VI  - 51
IP  - 8
DP  - 2003 Aug
TI  - Left ventricular mass index reduction early after an isolated aortic valve 
      replacement with St. Jude Medical 19A-HP.
PG  - 361-7
AB  - OBJECTIVES: It has been reported that the left ventricular mass index (LVMI) for 
      the hypertrophic myocardium is reduced at an early stage following surgery. In 
      this study, those factors affecting the changes in early postoperative LVMI were 
      investigated in cases in which a St. Jude Medical 19A-HP (19HP) mechanical heart 
      valve was used. METHODS: We studied 16 consecutive patients with pure aortic 
      stenosis undergoing isolated aortic valve replacement using a 19HP between 
      January 1994 and July 2001. The patients were all female, aged 64 +/- 6 years, 
      with a body surface area of 1.44 +/- 0.10 m2 and preoperative New York Heart 
      Association (NYHA) classification of 2.2 +/- 0.5. All patients underwent 
      transthoracic echocardiography at 4.2 +/- 3.3 days before and 16.3 +/- 10.2 days 
      after operation, and cardiac catheterization within a mean period of one month 
      before operation. The correlations between the decrease of LVMI at 16.3 +/- 10.2 
      days after operation and perioperative parameters were determined. RESULTS: There 
      was significant LVMI regression postoperatively (15 +/- 12%, p = 0.01), and only 
      a significant negative correlation between the decrease of LVMI and preoperative 
      left ventricular pressure (LVp) [r = -0.74, p < 0.01]. There was no effective 
      LVMI reduction in the high preoperative LVp group (> or = 210 mmHg). CONCLUSION: 
      It is expected that in the high LVp group, huge wall stress was being applied to 
      the left ventricular muscle immediately before surgery and in the early period 
      after surgery. Preoperative LVp is an important index for determining the 
      surgical timing and safe perioperative management. We recommend early surgical 
      treatment before LVp becomes more than 210 mmHg.
FAU - Uchikawa, Shin
AU  - Uchikawa S
AD  - Department of Cardiovascular Surgery, The Heart Institute of Japan, Tokyo Women's 
      Medical University, Tokyo, Japan.
FAU - Aomi, Shigeyuki
AU  - Aomi S
FAU - Kawai, Akihiko
AU  - Kawai A
FAU - Yamazaki, Kenji
AU  - Yamazaki K
FAU - Tomizawa, Yasuko
AU  - Tomizawa Y
FAU - Nishida, Hiroshi
AU  - Nishida H
FAU - Endo, Masahiro
AU  - Endo M
FAU - Koyanagi, Hitoshi
AU  - Koyanagi H
LA  - eng
PT  - Comparative Study
PT  - Evaluation Study
PT  - Journal Article
PL  - Japan
TA  - Jpn J Thorac Cardiovasc Surg
JT  - The Japanese journal of thoracic and cardiovascular surgery : official 
      publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka 
      Gakkai zasshi
JID - 100884261
RN  - 0 (Bretschneider cardioplegic solution)
RN  - 0 (Insulin)
RN  - 0 (glucose-insulin-potassium cardioplegic solution)
RN  - 3OWL53L36A (Mannitol)
RN  - 4Z8Y51M438 (Procaine)
RN  - 660YQ98I10 (Potassium Chloride)
RN  - IY9XDZ35W2 (Glucose)
RN  - RWP5GA015D (Potassium)
SB  - IM
MH  - Aged
MH  - Aortic Valve/physiopathology/*surgery
MH  - Female
MH  - Glucose/therapeutic use
MH  - Heart Valve Diseases/physiopathology/*surgery
MH  - Heart Valve Prosthesis Implantation/*instrumentation
MH  - Heart Ventricles/physiopathology/surgery
MH  - Humans
MH  - Insulin/therapeutic use
MH  - Japan
MH  - Mannitol/therapeutic use
MH  - Middle Aged
MH  - Potassium/therapeutic use
MH  - Potassium Chloride/therapeutic use
MH  - Procaine/therapeutic use
MH  - Prosthesis Design
MH  - Retrospective Studies
MH  - Statistics as Topic
MH  - Stroke Volume/physiology
MH  - Time Factors
MH  - Treatment Outcome
MH  - Ventricular Pressure/physiology
EDAT- 2003/09/10 05:00
MHDA- 2003/10/10 05:00
CRDT- 2003/09/10 05:00
PHST- 2003/09/10 05:00 [pubmed]
PHST- 2003/10/10 05:00 [medline]
PHST- 2003/09/10 05:00 [entrez]
AID - 10.1007/BF02719468 [doi]
PST - ppublish
SO  - Jpn J Thorac Cardiovasc Surg. 2003 Aug;51(8):361-7. doi: 10.1007/BF02719468.