PMID- 12966516
OWN - NLM
STAT- MEDLINE
DCOM- 20040105
LR  - 20061115
IS  - 0275-2565 (Print)
IS  - 0275-2565 (Linking)
VI  - 61
IP  - 1
DP  - 2003 Sep
TI  - Hematology of a natural population of toque macaques (Macaca sinica) at 
      polonnaruwa, Sri Lanka.
PG  - 13-28
AB  - Hematological studies were conducted in three wild groups of toque macaques 
      (Macaca sinica) inhabiting the Polonnaruwa Sanctuary in northeastern Sri Lanka. 
      The macaques were temporarily trapped and anesthetized, and femoral blood was 
      drawn from 35 males and 37 females (age range: 0.33-24.5 yr). Statistically 
      significant (P<0.05) differences were observed by sex for total plasma proteins 
      (PP), and by age for red blood cell (RBC) counts, hemoglobin (Hb), mean 
      corpuscular volume (MCV), mean corpuscular Hb (MCH), mean corpuscular Hb 
      concentration (MCHC), PP, erythrocyte sedimentation rate (ESR), differential and 
      absolute neutrophil counts, differential lymphocyte counts, and absolute 
      eosinophil counts. In general, the results were similar to those reported for 
      other species of colony-bred and free-ranging macaques. However, there also were 
      differences. First, in contrast to earlier studies of nonhuman primates, we 
      examined the hematology of infants. Compared to other age classes, infants (<1 yr 
      old) had lower RBC, Hb, MCHC, and ESR values, and a higher MCV. These findings 
      were similar to those obtained in human infants. Second, we observed variations 
      in hematology among social groups in relation to their ecology. Two groups (IH3 
      and M3) had ready access to water throughout the dry season (the period of 
      sampling), whereas the third group (J) did not. The Hb, RBC, and PP values 
      obtained in groups IH3 and M3 were similar to those reported in other macaque 
      species. However, these parameters in group J were significantly (P<0.01) higher, 
      which suggests that this group (representing about 26% of the sample) had been 
      dehydrated during the dry season. Finally, two indices indicative of injury and 
      infection--the ESR and leukocyte counts--were higher in the wild toque macaques 
      than has been reported for other species of macaques held in captivity, and about 
      15% of the toque macaques sampled had extreme outlier values for these 
      parameters; however, none were visibly ill or died. These results suggest that 
      wild toque macaques are subject to a wide array of physical and biological 
      insults that are unique to natural populations.
CI  - Copyright 2003 Wiley-Liss, Inc.
FAU - Ekanayake, Dilrukshi K
AU  - Ekanayake DK
AD  - Department of Veterinary Pathobiology, Faculty of Veterinary Medicine and Animal 
      Science, University of Peradeniya, Peradeniya, Sri Lanka.
FAU - Horadagoda, Neil U
AU  - Horadagoda NU
FAU - Sanjeevani, G K Madura
AU  - Sanjeevani GK
FAU - Arulkanthan, Appudurai
AU  - Arulkanthan A
FAU - Gunatilake, K A Sunil
AU  - Gunatilake KA
FAU - Dittus, Wolfgang P J
AU  - Dittus WP
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Am J Primatol
JT  - American journal of primatology
JID - 8108949
SB  - IM
MH  - Aging/*blood
MH  - Analysis of Variance
MH  - Animals
MH  - Female
MH  - Hematologic Tests
MH  - Macaca/*blood
MH  - Male
MH  - Reference Values
MH  - Sex Characteristics
MH  - Social Environment
MH  - Species Specificity
MH  - Sri Lanka
EDAT- 2003/09/11 05:00
MHDA- 2004/01/06 05:00
CRDT- 2003/09/11 05:00
PHST- 2003/09/11 05:00 [pubmed]
PHST- 2004/01/06 05:00 [medline]
PHST- 2003/09/11 05:00 [entrez]
AID - 10.1002/ajp.10105 [doi]
PST - ppublish
SO  - Am J Primatol. 2003 Sep;61(1):13-28. doi: 10.1002/ajp.10105.